Antioxidant and xanthine oxidase inhibitory activities of total polyphenols from onion.

Antioxidant and xanthine oxidase inhibitory activities of total polyphenols from onion.
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洋葱总多酚的抗氧化和黄嘌呤氧化酶抑制活性

DOI:
10.1016/j.sjbs.2017.08.005
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发表时间:
2018-11
影响因子:
4.4
通讯作者:
Deng H
Deng H
中科院分区:
生物学3区
文献类型:
--
作者:
Ouyang H;Hou K;Peng W;Liu Z;Deng H

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Onions (Allium cepa L.) comprise a valuable vegetable crop in many countries. Modern scientific research has shown that onions possess many biological activities, including antibacterial, anticancer, hypoglycemic, hypolipidemic, antiplatelet aggregation, and antioxidant activities. The goal of this study was to investigate the impact of total onion polyphenols on antioxidant and xanthine oxidase (XO) inhibitory activities. Total onion polyphenols showed significant antioxidant activity in DPPH, FRAP, and OH-assays (IC50 [µg/mL]), 43.24, 560.61, and 12.97, respectively). In a X/XO system, antioxidant properties of these polyphenols significantly inhibited XO activity (IC50 [µg/mL], 17.36). These results indicated that total onion polyphenols showed promising antioxidant and anti-gout properties and might be used as potential, natural drugs against oxidative diseases after successful studies in vivo as well as clinical trials.
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