Family income, parental education and brain structure in children and adolescents.
Family income, parental education and brain structure in children and adolescents.
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DOI：
10.1038/nn.3983
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发表时间：
2015-05
影响因子：
25
通讯作者：
Sowell, Elizabeth R.
中科院分区：
文献类型：
--
作者：
Noble, Kimberly G.;Houston, Suzanne M.;Brito, Natalie H.;Bartsch, Hauke;Kan, Eric;Kuperman, Joshua M.;Akshoomoff, Natacha;Amaral, David G.;Bloss, Cinnamon S.;Libiger, Ondrej;Schork, Nicholas J.;Murray, Sarah S.;Casey, B. J.;Chang, Linda;Ernst, Thomas M.;Frazier, Jean A.;Gruen, Jeffrey R.;Kennedy, David N.;Van Zijl, Peter;Mostofsky, Stewart;Kaufmann, Walter E.;Kenet, Tal;Dale, Anders M.;Jernigan, Terry L.;Sowell, Elizabeth R.
社会经济差异与认知发展的差异有关。这在多大程度上转化为大脑结构的差异尚不清楚。在这里，我们调查了社会经济因素和脑形态之间的关系，独立于遗传血统，在一个队列的1099个典型的发展个体之间的3和20年。收入与脑表面积有着密切的关系。具体而言，在来自低收入家庭的儿童中，收入的微小差异与表面积的相对较大差异相关，而在来自高收入家庭的儿童中，类似的收入增量与表面积的较小差异相关。这些关系在支持语言、阅读、执行功能和空间技能的区域中最为突出;表面积介导了某些神经认知能力的社会经济差异。这些数据表明，收入与最弱势儿童的大脑结构关系最密切。潜在的影响进行了讨论。
Socioeconomic disparities are associated with differences in cognitive development. The extent to which this translates to disparities in brain structure is unclear. Here, we investigated relationships between socioeconomic factors and brain morphometry, independently of genetic ancestry, among a cohort of 1099 typically developing individuals between 3 and 20 years. Income was logarithmically associated with brain surface area. Specifically, among children from lower income families, small differences in income were associated with relatively large differences in surface area, whereas, among children from higher income families, similar income increments were associated with smaller differences in surface area. These relationships were most prominent in regions supporting language, reading, executive functions and spatial skills; surface area mediated socioeconomic differences in certain neurocognitive abilities. These data indicate that income relates most strongly to brain structure among the most disadvantaged children. Potential implications are discussed.
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影响因子：
5.7
作者：
Chiang MC;McMahon KL;de Zubicaray GI;Martin NG;Hickie I;Toga AW;Wright MJ;Thompson PM
通讯作者：
Thompson PM
影响因子：
3.7
作者：
Hanson, Jamie L.;Hair, Nicole;Pollak, Seth D.
通讯作者：
Pollak, Seth D.
影响因子：
3
作者：
Alexander DH;Lange K
通讯作者：
Lange K
DOI：
10.1073/pnas.1208243109
发表时间：
2012-11-27
影响因子：
11.1
作者：
Fjell, Anders M.;Walhovd, Kristine Beate;Dale, Anders M.
通讯作者：
Dale, Anders M.
影响因子：
3.2
作者：
Klingberg, T;Forssberg, H;Westerberg, H
通讯作者：
Westerberg, H