Nanoparticles: Alternatives Against Drug-Resistant Pathogenic Microbes.
Nanoparticles: Alternatives Against Drug-Resistant Pathogenic Microbes.
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DOI：
10.3390/molecules21070836
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发表时间：
2016-06-27
期刊：
影响因子：
--
通讯作者：
Ghasemzadeh A
中科院分区：
文献类型：
--
作者：
Rudramurthy GR;Swamy MK;Sinniah UR;Ghasemzadeh A
Antimicrobial substances may be synthetic, semisynthetic, or of natural origin (i.e., from plants and animals). Antimicrobials are considered “miracle drugs” and can determine if an infected patient/animal recovers or dies. However, the misuse of antimicrobials has led to the development of multi-drug-resistant bacteria, which is one of the greatest challenges for healthcare practitioners and is a significant global threat. The major concern with the development of antimicrobial resistance is the spread of resistant organisms. The replacement of conventional antimicrobials by new technology to counteract antimicrobial resistance is ongoing. Nanotechnology-driven innovations provide hope for patients and practitioners in overcoming the problem of drug resistance. Nanomaterials have tremendous potential in both the medical and veterinary fields. Several nanostructures comprising metallic particles have been developed to counteract microbial pathogens. The effectiveness of nanoparticles (NPs) depends on the interaction between the microorganism and the NPs. The development of effective nanomaterials requires in-depth knowledge of the physicochemical properties of NPs and the biological aspects of microorganisms. However, the risks associated with using NPs in healthcare need to be addressed. The present review highlights the antimicrobial effects of various nanomaterials and their potential advantages, drawbacks, or side effects. In addition, this comprehensive information may be useful in the discovery of broad-spectrum antimicrobial drugs for use against multi-drug-resistant microbial pathogens in the near future.
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影响因子：
5.4
作者：
Arokiyaraj, S.;Saravanan, M.;Vincent, S.
通讯作者：
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影响因子：
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作者：
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影响因子：
2.5
作者：
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影响因子：
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作者：
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通讯作者：
Yang, Liju
DOI：
10.1155/2015/246012
发表时间：
2015
期刊：
Evidence-based complementary and alternative medicine : eCAM
影响因子：
--
作者：
Beyth N;Houri-Haddad Y;Domb A;Khan W;Hazan R
通讯作者：
Hazan R