Toward the Study of Trans-Disease Processes: A Novel Approach With Special Reference to the Study of Co-morbidity.

Toward the Study of Trans-Disease Processes: A Novel Approach With Special Reference to the Study of Co-morbidity.
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DOI:
10.1080/15504260902869147
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发表时间:
2009-04-01
影响因子:
2.2
通讯作者:
Mueller ET
Mueller ET
中科院分区:
医学4区
文献类型:
--
作者:
Bickel WK;Mueller ET

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本文的目的是提出一种新的方法,被称为跨疾病过程(TDPs)的研究,一般的疾病过程的神经科学研究,特别是共病。这种方法的特点进行了概述;一个潜在的TDP延迟折扣,这可能有助于解释吸烟和精神分裂症的共同发病率进行了探讨;和TDP的概念与内表型的概念进行了对比。技术发展方案有可能对科学产生各种积极影响。
The objective of this article was to propose a novel approach, referred to as the study of trans-disease processes (TDPs), to the neuroscientific study of disease processes in general and to co-morbid diseases in particular. The features of this approach are outlined; one potential TDP—delay discounting, which may help account for the co-morbidity of cigarette smoking and schizophrenia—is explored; and the concept of TDPs is contrasted with the concept of endophenotypes. TDPs have the potential for a variety of positive impacts on science.
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