Depression but not seizure factors or quality of life predicts suicidality in epilepsy.

Depression but not seizure factors or quality of life predicts suicidality in epilepsy.
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DOI:
10.1016/j.yebeh.2012.05.005
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发表时间:
2012-08
期刊:
Epilepsy & behavior : E&B
影响因子:
--
通讯作者:
Gilliam F
Gilliam F
中科院分区:
其他
文献类型:
--
作者:
Hecimovic H;Santos JM;Carter J;Attarian HP;Fessler AJ;Vahle V;Gilliam F

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目的是确定大样本癫痫门诊患者的自杀率和预测风险因素。我们前瞻性地检查了 193 名连续的成人癫痫门诊患者的抑郁情况,包括自杀意念。还评估了人口统计学和癫痫因素、药物毒性和健康相关的生活质量。过去两周内自杀意念的发生率为11.9%。尽管在双变量分析中药物毒性、健康相关生活质量和 BDI 评分均与自杀意念相关,但只有 BDI 在逻辑回归分析中仍然显着。大约四分之一有自杀意念的受试者没有明显的抑郁症状。最近的自杀想法在癫痫门诊中很常见,但不能通过性别、年龄、癫痫发作因素、药物毒性或自我感知的生活质量来预测。尽管抑郁症与自杀意念有关,但大约四分之一的自杀者情绪正常或仅有轻度抑郁。
The objective was to determine prevalence and predictive risk factors of suicidality in a large sample of epilepsy outpatients. We prospectively examined 193 consecutive adult epilepsy outpatients for depression, including suicidal ideation. Demographic and epilepsy factors, medication toxicity and health-related quality of life were also evaluated. The prevalence of suicidal ideation within the past two weeks was 11.9%. Although medication toxicity, health-related quality of life and BDI scores were each associated with suicidal ideation in the bivariate analyses, only the BDI remained significant in the logistic regression analysis. About one-fourth of the subjects with suicidal ideation had no significant symptoms of depression. Recent thoughts of suicide are a common occurrence in the outpatient epilepsy clinic setting, but are not predicted by gender, age, seizure factors, medication toxicity or self-perceived quality of life. Although depression is associated with suicidal ideation, about one-fourth of suicidal subjects was euthymic or only mildly depressed.
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