Periodic limb movements during sleep and risk of hypertension: A systematic review.
Periodic limb movements during sleep and risk of hypertension: A systematic review.
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DOI：
10.1016/j.sleep.2023.01.008
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发表时间：
2023-02
期刊：
影响因子：
4.8
通讯作者：
Cheungpasitporn, Wisit
中科院分区：
文献类型：
--
作者：
Srivali, Narat;Thongprayoon, Charat;Tangpanithandee, Supawit;Krisanapan, Pajaree;Mao, Michael A.;Zinchuk, Andrey;Koo, Brain B.;Cheungpasitporn, Wisit
多项研究表明睡眠期间周期性肢体运动 (PLMS) 与高血压之间存在关联。然而，缺乏对这种关系的系统评估。我们对报告比值比、相对风险、风险比或标准化发病率的观察性研究进行了系统回顾和荟萃分析，比较了 PLMS 患者（定义为每小时睡眠中周期性肢体运动水平，具体取决于个别研究）与未患 PLMS 患者的高血压风险。评估异质性和偏倚后，使用 DerSimonian 和 Laird 的随机效应、通用逆方差方法确定汇总风险比和 95% 置信区间 (CI)。在 572 篇潜在相关文章中，数据分析中纳入了 6 项符合条件的研究。研究（6 个横断面）包括 8,949 名参与者。本研究的统计异质性不显着，I2 为 0%。漏斗图和 Egger 回归不对称检验显示不存在发表偏倚，P 值≥ 0.05。 PLMS 患者高血压的汇总风险比为 1.26（95% CI，1.12-1.41）。我们的分析表明 PLMS 患者的高血压风险增加。需要前瞻性或干预性研究来证实这种关联。
Several studies suggest an association between periodic limb movements during sleep (PLMS) and hypertension; however, a systematic evaluation of this relationship is lacking. We conducted a systematic review and meta-analysis of observational studies that reported odds ratio, relative risk, hazard ratio, or standardized incidence ratio, comparing the risk of hypertension in persons with PLMS (defined by the level of periodic limb movements per hour of sleep depended on individual studies) versus those without PLMS. After assessing heterogeneity and bias, the pooled risk ratio and 95% confidence intervals (CIs) were determined using a random-effect, generic inverse variance method of DerSimonian and Laird. Out of 572 potentially relevant articles, six eligible studies were included in the data analysis. Studies (6 cross-sectional) included 8,949 participants. The statistical heterogeneity of this study was insignificant, with an I2 of 0%. A funnel plot and Egger’s regression asymmetry test showed no publication bias with P-value ≥ 0.05. The pooled risk ratio of hypertension in patients with PLMS was 1.26 (95% CI, 1.12–1.41). Our analysis demonstrates an increased hypertension risk among patients with PLMS. Prospective or interventional studies are needed to confirm this association.
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影响因子：
9.9
作者：
Budhiraja, Rohit;Javaheri, Sogol;Quan, Stuart F.
通讯作者：
Quan, Stuart F.
影响因子：
9.9
作者：
Pennestri, M. H.;Montplaisir, J.;Lanfranchi, P. A.
通讯作者：
Lanfranchi, P. A.
影响因子：
8.3
作者：
Fuchs, Flavio D.;Whelton, Paul K.
通讯作者：
Whelton, Paul K.
DOI：
10.1161/hypertensionaha.114.04193
发表时间：
2015-01
期刊：
Hypertension (Dallas, Tex. : 1979)
影响因子：
--
作者：
Koo BB;Sillau S;Dean DA 2nd;Lutsey PL;Redline S
通讯作者：
Redline S
DOI：
10.1016/0197-2456(86)90046-2
发表时间：
1986-09-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
DERSIMONIAN, R;LAIRD, N
通讯作者：
LAIRD, N