Rapid fabrication of electrochemical enzyme sensor chip using polydimethylsiloxane microfluidic channel
Rapid fabrication of electrochemical enzyme sensor chip using polydimethylsiloxane microfluidic channel
复制标题
利用聚二甲基硅氧烷微流通道快速制备电化学酶传感器芯片
DOI：
10.1016/s0003-2670(02)00634-7
复制
发表时间：
2002
影响因子：
6.2
通讯作者：
H. Misawa
中科院分区：
文献类型：
--
作者：
A. Yamaguchi;Peng Jin;H. Tsuchiyama;T. Masuda;K. Sun;S. Matsuo;H. Misawa
聚二甲基硅氧烷（PDMS）的酶传感器芯片的简单和快速的制造，基于电化学检测的适用性进行了检查。该传感器芯片由PDMS基片和玻璃基片组成，PDMS基片上制作有微流控通道，玻璃基片上制作有酶修饰的微电极。两个基板被夹在塑料板之间。在连续溶液流量（34μl/min）下，传感器芯片显示微电极周围无泄漏。在这项工作中开发的传感器芯片的电流响应表明，各种类型的酶传感器可以通过使用PDMS微流体通道设计。
Applicability of polydimethylsiloxane (PDMS) for easy and rapid fabrication of enzyme sensor chips, based on electrochemical detection, is examined. The sensor chip consists of PDMS substrate with a microfluidic channel fabricated in it, and a glass substrate with enzyme-modified microelectrodes. The two substrates are clamped together between plastic plates. The sensor chip has shown no leakage around the microelectrodes under continuous solution flow (34μl/min). Amperometric response of the sensor chips developed in this work suggest that various types of enzyme sensors can be designed by using PDMS microfluidic channels.
影响因子：
7.4
作者：
Anderson, JR;Chiu, DT;Whitesides, GM
通讯作者：
Whitesides, GM
DOI：
10.1073/pnas.96.10.5545
发表时间：
1999-05-11
影响因子：
11.1
作者：
Takayama, S;McDonald, JC;Whitesides, GM
通讯作者：
Whitesides, GM