Parallel recruitment of multiple genes into c4 photosynthesis.
Parallel recruitment of multiple genes into c4 photosynthesis.
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DOI：
10.1093/gbe/evt168
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发表时间：
2013
影响因子：
3.3
通讯作者：
Osborne CP
中科院分区：
文献类型：
--
作者：
Christin PA;Boxall SF;Gregory R;Edwards EJ;Hartwell J;Osborne CP
在生物体的多样化过程中，新的适应性特征通常通过先前存在的基因的共同选择而进化。然而，大多数酶是由基因家族编码的，其成员的表达和催化特性各不相同。因此，每个人在招募新职能的适合性方面可能有所不同。在这项工作中，我们以 C4 光合作用为例来测试这种基因招募偏差的存在，C4 光合作用是一种复杂的性状，作为对大气二氧化碳消耗的反应，在开花植物中反复进化。我们结合了对独立进化出 C4 性状的三种草种的完整核基因组和高通量转录组数据的分析。对于分析的七种酶中的五种，尽管存在多个拷贝，但在独立的 C4 起源上招募了相同的基因谱系。对密切相关的 C3 草的分析证实，C4 表达模式并不存在于 C3 祖先中，而是在向 C4 光合作用的进化过渡过程中获得的。基因招募中的显着偏差表明某些基因更适合新功能，可能是因为它们积累的突变使它们更接近新功能所需的特征。
During the diversification of living organisms, novel adaptive traits usually evolve through the co-option of preexisting genes. However, most enzymes are encoded by gene families, whose members vary in their expression and catalytic properties. Each may therefore differ in its suitability for recruitment into a novel function. In this work, we test for the presence of such a gene recruitment bias using the example of C4 photosynthesis, a complex trait that evolved recurrently in flowering plants as a response to atmospheric CO2 depletion. We combined the analysis of complete nuclear genomes and high-throughput transcriptome data for three grass species that evolved the C4 trait independently. For five of the seven enzymes analyzed, the same gene lineage was recruited across the independent C4 origins, despite the existence of multiple copies. The analysis of a closely related C3 grass confirmed that C4 expression patterns were not present in the C3 ancestors but were acquired during the evolutionary transition to C4 photosynthesis. The significant bias in gene recruitment indicates that some genes are more suitable for a novel function, probably because the mutations they accumulated brought them closer to the characteristics required for the new function.
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