Treatment of seasonal affective disorder with green light and red light.
Treatment of seasonal affective disorder with green light and red light.
复制标题
用绿光和红光治疗季节性情感障碍。
DOI：
10.1176/ajp.148.4.509
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发表时间：
1991
期刊：
影响因子：
--
通讯作者：
Rosenthal,NE
中科院分区：
文献类型：
--
作者：
Oren,DA;Brainard,GC;Johnston,SH;Joseph-Vanderpool,JR;Sorek,E;Rosenthal,NE
本研究旨在确定是否相等的光子密度的绿色光是上级红光治疗季节性情感disorder.Methodafter招聘通过媒体，20名门诊患者与季节性情感障碍参加了平衡的顺序交叉试验的1周的绿色光治疗相比，1周的红光治疗。每次治疗包括每天清晨在家进行2小时的光照治疗。两种处理条件均排除紫外光。两种治疗的光子密度（2.3 × 10（15）光子/秒/cm 2）与先前使用2500勒克斯白色光治疗的研究中使用的光子密度相似。14名患者完成了研究。每个治疗期至少间隔1周，以留出复发时间。治疗的有效性进行了评估，通过方差分析的等级变化的汉密尔顿评定量表Depress.ResultsAlthough患者的期望的两种治疗方法是相似的，绿色光诱导更大的抗抑郁作用比红光。一个序列的颜色interaction也demonstrated.ConclusionsGreen光提供了一个治疗效果上级的红光和类似的白色光在以前的研究中看到的。这些结果与季节性情感障碍中视网膜光感受器介导抗抑郁反应的假设一致。确定光治疗的最佳波长对于优化光疗功效非常重要。
ObjectiveThis study sought to determine whether an equal photon density of green light is superior to red light in treating seasonal affective disorder.MethodAfter recruitment through the media, 20 outpatients with seasonal affective disorder participated in a balanced-order crossover trial of 1 week of green light therapy compared with 1 week of red light therapy. Each treatment consisted of 2 hours of daily light treatment at home in the early morning. Ultraviolet light was excluded from both treatment conditions. The photon densities of the two treatments (2.3 x 10 (15) photons/sec per cm2) were similar to those used in previous studies of therapy with 2500-lux white light. Fourteen patients completed the study. At least 1 week separated each treatment period to allow time for relapse. Effectiveness of treatment was assessed by analysis of variance of changes in ratings on the Hamilton Rating Scale for Depression.ResultsAlthough patients' expectations of the two treatments were similar, green light induced greater antidepressant effects than red light. A Sequence by Color interaction was also demonstrated.ConclusionsGreen light provides a treatment effect superior to that of red light and similar to that seen in previous studies with white light. These results are consistent with the hypothesis that retinal photoreceptors mediate the antidepressant response in seasonal affective disorder. Identifying optimal wavelengths for light treatment is important in optimizing phototherapy efficacy.
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影响因子：
6.6
作者：
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通讯作者：
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