Physical approaches to biomaterial design.
Physical approaches to biomaterial design.
复制标题
作者：
用于药物递送、组织工程和医学诊断的生物材料的开发传统上基于新的化学。然而，人们越来越认识到，材料的物理和化学性质可以调节生物反应。在这里，我们回顾这种过渡方面选定的物理性能，包括大小，形状，机械性能，表面纹理和划分。在每一种情况下，我们提出的例子证明这些属性在生物学中的意义。我们还讨论了设计生物材料的合成方法和生物应用，这些材料具有独特的物理特性。
The development of biomaterials for drug delivery, tissue engineering and medical diagnostics has traditionally been based on new chemistries. However, there is growing recognition that the physical as well as the chemical properties of materials can regulate biological responses. Here, we review this transition with regard to selected physical properties including size, shape, mechanical properties, surface texture and compartmentalization. In each case, we present examples demonstrating the significance of these properties in biology. We also discuss synthesis methods and biological applications for designer biomaterials, which offer unique physical properties.
登录
查看更多内容
影响因子：
4.9
作者：
Alexis F;Pridgen E;Molnar LK;Farokhzad OC
通讯作者：
Farokhzad OC
影响因子：
4.9
作者：
Cayre, O;Paunov, VN;Velev, OD
通讯作者：
Velev, OD
影响因子：
3.7
作者：
Dalby, MJ;Berry, CC;Curtis, ASG
通讯作者：
Curtis, ASG
影响因子：
10.8
作者：
Champion, Julie A.;Katare, Yogesh K.;Mitragotri, Samir
通讯作者：
Mitragotri, Samir
影响因子：
1.7
作者：
BASINSKA, T;SLOMKOWSKI, S;DELAMAR, M
通讯作者：
DELAMAR, M