Common and distinct networks underlying reward valence and processing stages: a meta-analysis of functional neuroimaging studies.
Common and distinct networks underlying reward valence and processing stages: a meta-analysis of functional neuroimaging studies.
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DOI：
10.1016/j.neubiorev.2010.12.012
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发表时间：
2011-04
影响因子：
8.2
通讯作者：
Fan, Jin
中科院分区：
文献类型：
--
作者：
Liu, Xun;Hairston, Jacqueline;Schrier, Madeleine;Fan, Jin
关键词：
为了更好地了解人类大脑中的奖励回路，我们对142项神经成像研究进行了激活似然估计（ALE）和基于参数体素的荟萃分析（PVM），这些研究检查了健康成年人在奖励相关任务中的大脑激活。我们观察了几个参与奖励相关决策的核心脑区，包括丘脑核（NAcc），尾状核，壳核，丘脑，眶额皮层（OFC），双侧前扣带皮层，前扣带皮层（ACC）和后扣带皮层（PCC），以及顶下小叶和前额叶皮层（PFC）的认知控制区域。NAcc通常在奖励处理的各个阶段被积极和消极奖励激活（例如，预测、结果和评价）。此外，内侧OFC和PCC优先响应积极奖励，而ACC，双侧前额叶皮层和外侧PFC选择性地响应负奖励。奖励预期激活了ACC、双侧前额叶和脑干，而奖励结果更显著地激活了NAcc、内侧OFC和杏仁核。因此，奖励相关决策的神经生物学理论应该考虑奖励评价和效价评估的分布和相关表征。
To better understand the reward circuitry in human brain, we conducted activation likelihood estimation (ALE) and parametric voxel-based meta-analyses (PVM) on 142 neuroimaging studies that examined brain activation in reward-related tasks in healthy adults. We observed several core brain areas that participated in reward-related decision making, including the nucleus accumbens (NAcc), caudate, putamen, thalamus, orbitofrontal cortex (OFC), bilateral anterior insula, anterior (ACC) and posterior (PCC) cingulate cortex, as well as cognitive control regions in the inferior parietal lobule and prefrontal cortex (PFC). The NAcc was commonly activated by both positive and negative rewards across various stages of reward processing (e.g., anticipation, outcome, and evaluation). In addition, the medial OFC and PCC preferentially responded to positive rewards, whereas the ACC, bilateral anterior insula, and lateral PFC selectively responded to negative rewards. Reward anticipation activated the ACC, bilateral anterior insula, and brain stem, whereas reward outcome more significantly activated the NAcc, medial OFC, and amygdala. Neurobiological theories of reward-related decision making should therefore distributed and interrelated representations of reward valuation and valence assessment into account.
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影响因子：
4.8
作者：
Eickhoff, Simon B.;Laird, Angela R.;Grefkes, Christian;Wang, Ling E.;Zilles, Karl;Fox, Peter T.
通讯作者：
Fox, Peter T.
DOI：
10.1073/pnas.0504136102
发表时间：
2005-07-05
影响因子：
11.1
作者：
Fox, MD;Snyder, AZ;Raichle, ME
通讯作者：
Raichle, ME
影响因子：
5.3
作者：
Bjork, JM;Knutson, B;Hommer, DW
通讯作者：
Hommer, DW
影响因子：
2.9
作者：
Cohen, MX;Ranganath, C
通讯作者：
Ranganath, C
DOI：
10.1523/jneurosci.4578-08.2009
发表时间：
2009-02-11
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Bach DR;Seymour B;Dolan RJ
通讯作者：
Dolan RJ