Gold nanoparticle platforms as drug and biomacromolecule delivery systems.

Gold nanoparticle platforms as drug and biomacromolecule delivery systems.
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DOI:
10.1016/j.jconrel.2010.06.004
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发表时间:
2010-11-20
期刊:
Journal of controlled release : official journal of the Controlled Release Society
影响因子:
--
通讯作者:
Rotello VM
Rotello VM
中科院分区:
其他
文献类型:
--
作者:
Duncan B;Kim C;Rotello VM

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金纳米粒子(AuNPs)是开发高效递送系统的合适平台。金纳米粒子易于合成、功能化,且具有生物相容性。金纳米粒子单分子层的可调性使得能够完全控制这些纳米载体的表面性质,以实现靶向以及稳定性/释放。这篇综述将讨论几种利用金纳米粒子的递送策略。
Gold nanoparticles (AuNPs) are a suitable platform for development of efficient delivery systems. AuNPs can be easily synthesized, functionalized, and are biocompatible. The tunability of the AuNP monolayer allows for complete control of surface properties for targeting and stability/release using these nanocarriers. This review will discuss several delivery strategies utilizing AuNPs.
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