Northward genetic penetration across the Himalayas viewed from Sherpa people

Northward genetic penetration across the Himalayas viewed from Sherpa people
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从夏尔巴人的角度看喜马拉雅山脉向北的基因渗透

DOI:
10.3109/19401736.2014.895986
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发表时间:
2016-01
期刊:
影响因子:
--
通讯作者:
Hui Li*
Hui Li*
中科院分区:
生物4区
文献类型:
--
作者:
Feng Chen;Dali Yao;Li Jin;Hui Li*

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摘要 喜马拉雅山脉被认为是人类迁徙的天然屏障,特别是从印度次大陆向北扩散到青藏高原的过程。然而,尽管大多数夏尔巴人有藏缅血统,但在生活在西藏的夏尔巴人中观察到相当多来自印度次大陆的遗传成分。西方 Y 染色体单倍群 R1a1a-M17、J-M304 和 F*-M89 几乎占夏尔巴人父系基因库的 17%。在母系方面,来自西部的M5c2、M21d和U也占夏尔巴人的8%。这些起源于南亚的谱系表明喜马拉雅山已经可以渗透双向基因流。
Abstract The Himalayas have been suggested as a natural barrier for human migrations, especially the northward dispersals from the Indian Subcontinent to Tibetan Plateau. However, although the majority of Sherpa have a Tibeto-Burman origin, considerable genetic components from Indian Subcontinent have been observed in Sherpa people living in Tibet. The western Y chromosomal haplogroups R1a1a-M17, J-M304, and F*-M89 comprise almost 17% of Sherpa paternal gene pool. In the maternal side, M5c2, M21d, and U from the west also count up to 8% of Sherpa people. Those lineages with South Asian origin indicate that the Himalayas have been permeable to bidirectional gene flow.
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