One-month IOP in mitomycin C-augmented trabeculectomy can predict long-term IOP control in chronic primary angle-closure glaucoma
One-month IOP in mitomycin C-augmented trabeculectomy can predict long-term IOP control in chronic primary angle-closure glaucoma
复制标题
丝裂霉素 C 增强小梁切除术中一个月的眼压可以预测慢性原发性闭角型青光眼的长期眼压控制
DOI：
10.1007/s10792-019-01072-1
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发表时间：
2019-01
影响因子：
1.6
通讯作者：
Ge Jian
中科院分区：
文献类型：
--
作者：
Zuo Chengguo;Lin Shufen;Wu Keling;Gong Ruowen;Liu Yafen;Lin Mingkai;Ge Jian
目的探讨原发性闭角型青光眼（CPACG）行原发性小梁切除术后长期眼压（IOP）的影响因素。方法系统回顾原发性小梁切除术治疗CPACG的病例。所有病例的巩膜瓣均采用两根原位缝线和两根可释放缝线缝合，以确保术中正常IOP条件下的水密性。所有眼均应用丝裂霉素C。所有患者随访2年。根据眼压和滤泡的形状，对眼球进行数字按摩并拆除可释放缝线。记录人口统计数据和临床结果。确定预测长期IOP的因素。结果共纳入患者72例（88眼），平均年龄58.51±10.60岁。术后2年全成功率89.77%。IOP在7天后开始稳定，并在随访1个月时达到最低点。术前、术后早期高眼压或低眼压不影响远期疗效（P < 0.05）。术后随访1个月和2年IOP呈正相关（r= 0.64，P< 0.001）。结论原发性小梁切除术CPACG患者，在正常IOP条件下，巩膜瓣原位缝合2针、松开2针水紧密缝合，可确保CPACG治疗可控、有效、安全。术前和术后早期的高眼压或低眼压不影响远期疗效。术后1个月的IOP可作为长期IOP控制的预测指标。
PurposeTo investigate the predictors of long-term intraocular pressure (IOP) in chronic primary angle-closure glaucoma (CPACG) treated with primary trabeculectomy.MethodsThis study systematically reviewed cases of CPACG treated with primary trabeculectomy. The scleral flaps in all cases were sutured with two stitches in situ and two releasable sutures to ensure watertight under normal IOP conditions during surgery. Mitomycin C was used in all eyes. All patients were followed for 2 years. Digital massage of the bulbus and removal of the releasable suture were performed according to the IOP and shape of the filtering bleb. Demographic data and clinical outcomes were recorded. Factors predicting long-term IOP were identified.ResultsA total of 72 patients (88 eyes) with a mean age of 58.51 ± 10.60 years were included in this study. The complete success rate was 89.77% after 2 years. The IOP began to stabilize after 7 days and reached its lowest point at the 1-month follow-up. The preoperative and early postoperative high or low IOP does not affect long-term effects (P> 0.05). There was a positive correlation between postoperative IOP at the 1-month and 2-year follow-ups (r= 0.64,P< 0.001).ConclusionIn CPACG patients undergoing primary trabeculectomy, scleral flaps sutured watertightly with two stitches in situ and two releasable sutures under normal IOP conditions can ensure controllable, effective and safe treatment of CPACG. The preoperative and early postoperative high or low IOP does not affect long-term effects. One-month postoperative IOP can be used as a predictor of long-term IOP control.
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影响因子：
2
作者：
Schwenn, O;Kersten, I;Pfeiffer, N
通讯作者：
Pfeiffer, N
影响因子：
3.9
作者：
S. Rong;S. Rong;M. Feng;Ningli Wang;H. Meng;Ravi Thomas;S. Fan;R. Wang;X. Wang;X. Tang;Yuanbo Liang;Yuanbo Liang
通讯作者：
S. Rong;S. Rong;M. Feng;Ningli Wang;H. Meng;Ravi Thomas;S. Fan;R. Wang;X. Wang;X. Tang;Yuanbo Liang;Yuanbo Liang
影响因子：
2
作者：
L. Polikoff;A. Taglienti;R. Chanis;J. Ramos-Esteban;Nicholas Donas;J. Tsong;D. J. Gagliuso;J. Danias;J. Serle
通讯作者：
L. Polikoff;A. Taglienti;R. Chanis;J. Ramos-Esteban;Nicholas Donas;J. Tsong;D. J. Gagliuso;J. Danias;J. Serle
影响因子：
2
作者：
Okimoto, Satoshi;Kiuchi, Yoshiaki;Tanaka, Junko
通讯作者：
Tanaka, Junko
影响因子：
4.4
作者：
Liang, Yuanbo;Friedman, David S.;Wang, Ning Li
通讯作者：
Wang, Ning Li