Roles of the calcified cartilage layer and its tissue engineering reconstruction in osteoarthritis treatment.
Roles of the calcified cartilage layer and its tissue engineering reconstruction in osteoarthritis treatment.
复制标题
钙化软骨层及其组织工程重建在骨关节炎治疗中的作用
DOI：
10.3389/fbioe.2022.911281
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发表时间：
2022
影响因子：
5.7
通讯作者：
Zhou, Yang
中科院分区：
文献类型：
--
作者：
Wang, Weiyang;Ye, Ruixi;Xie, Wenqing;Zhang, Yueyao;An, Senbo;Li, Yusheng;Zhou, Yang
Sandwiched between articular cartilage and subchondral bone, the calcified cartilage layer (CCL) takes on both biomechanical and biochemical functions in joint development and ordinary activities. The formation of CCL is not only unique in articular cartilage but can also be found in the chondro-osseous junction adjacent to the growth plate during adolescence. The formation of CCL is an active process under both cellular regulation and intercellular communication. Abnormal alterations of CCL can be indications of degenerative diseases including osteoarthritis. Owing to the limited self-repair capability of articular cartilage and core status of CCL in microenvironment maintenance, tissue engineering reconstruction of CCL in damaged cartilage can be of great significance. This review focuses on possible tissue engineering reconstruction methods targeting CCL for further OA treatment.
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影响因子：
3.3
作者：
Sophia Fox AJ;Bedi A;Rodeo SA
通讯作者：
Rodeo SA
DOI：
10.1302/0301-620x.65b1.6337169
发表时间：
1983-01-01
影响因子：
--
作者：
BULLOUGH, PG;JAGANNATH, A
通讯作者：
JAGANNATH, A
影响因子：
27.4
作者：
FAWNS, HT;LANDELLS, JW
通讯作者：
LANDELLS, JW
影响因子：
7
作者：
Bertuglia, A.;Lacourt, M.;Laverty, S.
通讯作者：
Laverty, S.
影响因子：
14
作者：
Cheng, Hiu-Wa;Luk, Keith D. K.;Chan, Barbara P.
通讯作者：
Chan, Barbara P.