Non-contrast-enhanced flow-independent peripheral MR angiography with balanced SSFP.

Non-contrast-enhanced flow-independent peripheral MR angiography with balanced SSFP.
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DOI:
10.1002/mrm.21921
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发表时间:
2009-06
影响因子:
3.3
通讯作者:
Nishimura DG
Nishimura DG
中科院分区:
医学3区
文献类型:
--
作者:
Cukur T;Lee JH;Bangerter NK;Hargreaves BA;Nishimura DG

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血流非依赖性血管造影术是一种非对比剂增强的技术,即使在下肢血流量减少的情况下也能产生血管造影剂。提出了一种用磁化制备的平衡稳态自由进动(BSSFP)制作这种血管成像的方法。因为bSSFP产生明亮的脂肪信号,所以强有力的脂肪抑制对于详细描述血管系统是必不可少的。因此,已经研究了几种策略来提高短扫描时间内脂肪抑制的可靠性。相敏(PS)SSFP可以有效地抑制脂肪,但由于脂肪和水占据同一体素而产生的部分体积效应会导致血液信号的丢失。相反,交替重复时间(ATR)SSFP将这种损失降至最低;然而,抑制水平受场不均匀的影响。最后,一种新的双捕获ATR-SSFP技术降低了这种对非共振的敏感性。活体实验结果表明,当部分体积效应显著时,这两种基于ATR的技术提供了更可靠的对比。
Flow-independent angiography is a non-contrast-enhanced technique that can generate vessel contrast even with reduced blood flow in the lower extremities. A method is presented for producing these angiograms with magnetization-prepared balanced steady-state free precession (bSSFP). Because bSSFP yields bright fat signal, robust fat suppression is essential for detailed depiction of the vasculature. Therefore, several strategies have been investigated to improve the reliability of fat suppression within short scan times. Phase-sensitive (PS) SSFP can efficiently suppress fat; however, partial volume effects due to fat and water occupying the same voxel can lead to the loss of blood signal. In contrast, alternating repetition time (ATR) SSFP minimizes this loss; however, the level of suppression is compromised by field inhomogeneity. Finally, a new double-acquisition ATR-SSFP technique reduces this sensitivity to off-resonance. In vivo results indicate that the two ATR-based techniques provide more reliable contrast when partial volume effects are significant.
DOI: 10.1002/jmri.1880070405
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期刊: JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING
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