Chronic and acute stress and the prediction of major depression in women.
Chronic and acute stress and the prediction of major depression in women.
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DOI：
10.1002/da.20571
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发表时间：
2009
影响因子：
7.4
通讯作者：
Brennan, Patricia A.
中科院分区：
文献类型：
--
作者：
Hammen, Constance;Kim, Eunice Y.;Eberhart, Nicole K.;Brennan, Patricia A.
本研究探讨了相对被忽视的作用，慢性压力在重性抑郁症，检查独立的贡献，共同发生的慢性和急性压力抑郁症，慢性压力是否预测急性生活事件，以及两种类型的压力是否相互作用，使更大的慢性压力赋予更大的敏感性或抵抗力的抑郁影响的急性压力。从816名社区妇女的样本中，那些在过去9个月内有严重抑郁发作的人和那些没有严重抑郁发作（MDE）发作，没有当前或最近的心境恶劣障碍病史的人进行了比较，基于访谈的措施，先行的急性和慢性压力。慢性压力访谈客观压力在多个日常角色域，和急性压力进行了评估与上下文威胁访谈。MDE发作与慢性和急性应激显著相关;慢性应激也与急性事件的发生相关，并且有一种趋势表明，急性应激增加与高慢性应激与低慢性应激的抑郁症相关性更强。结果表明，包括评估慢性压力的重要性，在充分了解的程度和机制的压力抑郁症的关系。
This study explored the relatively neglected role of chronic stress in major depression, examining the independent contributions of co-occurring chronic and acute stress to depression, whether chronic stress predicts acute life events, and whether the two types of stress interact such that greater chronic stress confers greater sensitivity—or resistance—to the depressive effects of acute stressors. From a sample of 816 community women, those who had a major depression onset in the past 9 months and those without major depressive episodes (MDE) onset and with no history of current or recent dysthymic disorder were compared on interview-based measures of antecedent acute and chronic stress. Chronic stress interviews rated objective stress in multiple everyday role domains, and acute stress was evaluated with contextual threat interviews. MDE onset was significantly associated with both chronic and acute stress; chronic stress was also associated with the occurrence of acute events, and there was a trend suggesting that increased acute stress is more strongly associated with depression in those with high versus low chronic stress. Results suggest the importance of including assessment of chronic stress in fully understanding the extent and mechanisms of stress–depression relationships.
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影响因子：
5.4
作者：
Monroe, SM;Harkness, KL
通讯作者：
Harkness, KL
影响因子：
6.6
作者：
Hammen, C;Brennan, PA
通讯作者：
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作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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