The biology of influenza viruses.
The biology of influenza viruses.
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DOI:
10.1016/j.vaccine.2008.07.039
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发表时间:
2008-09-12
期刊:
影响因子:
5.5
通讯作者:
Palese P
中科院分区:
文献类型:
--
作者:
Bouvier NM;Palese P
The influenza viruses are characterized by segmented, negative-strand RNA genomes requiring an RNA-dependent RNA polymerase of viral origin for replication. The particular structure of the influenza virus genome and function of its viral proteins enable antigenic drift and antigenic shift. These processes result in viruses able to evade the long-term adaptive immune responses in many hosts.
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