What does a neuron learn from multisensory experience?
What does a neuron learn from multisensory experience?
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神经元从多感官体验中学到什么？
DOI：
10.1152/jn.00284.2014
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发表时间：
2015-02
影响因子：
2.5
通讯作者：
Stein Barry E.
中科院分区：
文献类型：
--
作者：
Xu Jinghong;Yu Liping;Stanford Terrence R.;Rowl;Benjamin A.;Stein Barry E.
大脑整合来自不同感官的信息的能力是在广泛的感官体验之后获得的。然而，早期生活经历是否体现了多感觉神经元的一般整合能力，还是仅限于所接触的特定跨模式刺激组合的能力，尚不清楚。通过在生命的最初几个月选择性地限制视觉-非视觉或听觉-非听觉体验，本研究发现猫上丘中的三感觉神经元（以及它们的双感觉对应物）变得适应了每种饲养环境特有的跨模式刺激组合。因此，即使在成熟时，三感觉神经元也不会整合它们能够响应的所有跨模式刺激组合，而只会整合那些通过经验联系起来以构成连贯时空事件的组合。这种选择性的成熟过程决定了哪些环境事件将成为上丘介导的注意力和方向转变的最有效目标。
The brain's ability to integrate information from different senses is acquired only after extensive sensory experience. However, whether early life experience instantiates a general integrative capacity in multisensory neurons or one limited to the particular cross-modal stimulus combinations to which one has been exposed is not known. By selectively restricting either visual-nonvisual or auditory-nonauditory experience during the first few months of life, the present study found that trisensory neurons in cat superior colliculus (as well as their bisensory counterparts) became adapted to the cross-modal stimulus combinations specific to each rearing environment. Thus, even at maturity, trisensory neurons did not integrate all cross-modal stimulus combinations to which they were capable of responding, but only those that had been linked via experience to constitute a coherent spatiotemporal event. This selective maturational process determines which environmental events will become the most effective targets for superior colliculus-mediated shifts of attention and orientation.
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DOI：
10.1523/jneurosci.5575-09.2010
发表时间：
2010-04-07
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Yu L;Rowland BA;Stein BE
通讯作者：
Stein BE
DOI：
10.1523/jneurosci.4304-11.2012
发表时间：
2012-02-15
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Xu J;Yu L;Rowland BA;Stanford TR;Stein BE
通讯作者：
Stein BE
影响因子：
--
作者：
A. King;J. Schnupp;S. Carlile;Adam L. Smith;I. Thompson
通讯作者：
A. King;J. Schnupp;S. Carlile;Adam L. Smith;I. Thompson
影响因子：
56.9
作者：
MEREDITH, MA;STEIN, BE
通讯作者：
STEIN, BE
影响因子：
2.9
作者：
Patton, PE;Anastasio, TJ
通讯作者：
Anastasio, TJ