Non-invasive computation of aortic pressure maps: a phantom-based study of two approaches
Non-invasive computation of aortic pressure maps: a phantom-based study of two approaches
复制标题
主动脉压力图的无创计算:两种方法的基于模型的研究
DOI:
10.1117/12.2043208
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发表时间:
2014
期刊:
影响因子:
--
通讯作者:
R. Unterhinninghofen
中科院分区:
文献类型:
--
作者:
M. Delles;S. Schalck;Y. Chassein;T. Müller;F. Rengier;S. Speidel;H. von Tengg- Kobligk;H.-U. Kauczor;R. Dillmann;R. Unterhinninghofen
Patient-specific blood pressure values in the human aorta are an important parameter in the management of cardiovascular diseases. A direct measurement of these values is only possible by invasive catheterization at a limited number of measurement sites. To overcome these drawbacks, two non-invasive approaches of computing patient-specific relative aortic blood pressure maps throughout the entire aortic vessel volume are investigated by our group. The first approach uses computations from complete time-resolved, three-dimensional flow velocity fields acquired by phasecontrast magnetic resonance imaging (PC-MRI), whereas the second approach relies on computational fluid dynamics (CFD) simulations with ultrasound-based boundary conditions. A detailed evaluation of these computational methods under realistic conditions is necessary in order to investigate their overall robustness and accuracy as well as their sensitivity to certain algorithmic parameters. We present a comparative study of the two blood pressure computation methods in an experimental phantom setup, which mimics a simplified thoracic aorta. The comparative analysis includes the investigation of the impact of algorithmic parameters on the MRI-based blood pressure computation and the impact of extracting pressure maps in a voxel grid from the CFD simulations. Overall, a very good agreement between the results of the two computational approaches can be observed despite the fact that both methods used completely separate measurements as input data. Therefore, the comparative study of the presented work indicates that both non-invasive pressure computation methods show an excellent robustness and accuracy and can therefore be used for research purposes in the management of cardiovascular diseases.
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DOI:
10.1007/11505730_36
发表时间:
2005-07
期刊:
Information processing in medical imaging : proceedings of the ... conference
影响因子:
--
作者:
Yuehuang Wang;A. Amini
通讯作者:
Yuehuang Wang;A. Amini
影响因子:
3.5
作者:
Yuehuang Wang;A. Moghaddam;G. Behrens;N. Fatouraee;J. Cebral;E. Choi;A. Amini
通讯作者:
A. Amini
DOI:
10.1098/rstb.2007.2119
发表时间:
2007
期刊:
Philosophical Transactions of the Royal Society B: Biological Sciences
影响因子:
--
作者:
Guang;R. Merrifield;S. Masood;P. Kilner
通讯作者:
P. Kilner
影响因子:
3.3
作者:
Yang, GZ;Kilner, PJ;Firmin, DN
通讯作者:
Firmin, DN
DOI:
10.1115/1.1468866
发表时间:
2002-06-01
影响因子:
1.7
作者:
Ebbers, T;Wigström, L;Karlsson, M
通讯作者:
Karlsson, M