Maternal postnatal depression and child growth: a European cohort study.
Maternal postnatal depression and child growth: a European cohort study.
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DOI：
10.1186/1471-2431-10-14
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发表时间：
2010-03-12
期刊：
影响因子：
2.4
通讯作者：
European Childhood Obesity Trial Study Group
中科院分区：
文献类型：
--
作者：
Grote V;Vik T;von Kries R;Luque V;Socha J;Verduci E;Carlier C;Koletzko B;European Childhood Obesity Trial Study Group
以前的研究已经报道了产后抑郁对婴儿早期生长的积极和消极影响。这项研究检验了一种假设，即母亲产后抑郁可能是日后儿童发育迟缓或超重的一个风险因素。共有929名妇女和她们的孩子参加了一项欧洲多中心研究，平均年龄为14天。母亲在分娩后2、3和6个月完成爱丁堡产后抑郁量表（EPDS）。EPDS评分在任何时间均为13分及以上者为产妇抑郁症。测量体重、长度、肱三头肌和肩胛下皮褶厚度，并在儿童两岁时计算体重指数（BMI），并根据世卫组织多中心生长参考研究（MGRS）将其转换为标准差分数。EPDS得分高的母亲所生婴儿的体重长度z分数（-0.55,SD 0.74）低于得分正常的母亲（-0.36,SD 0.74; p = 0.013）。24月龄BMI在高EPDS组（16.3 kg/m2, SD 1.3）和正常EPDS组（16.2 kg/m2, SD 1.3; p = 0.48）之间没有差异。所有其他人体测量指标在两组之间也没有差异，没有多变量调整的变化。我们得出结论，在高收入国家，高母亲产后抑郁评分对后代的生长没有任何重大影响。
Previous studies have reported postpartum depression to be associated with both positive and negative effects on early infant growth. This study examined the hypothesis that maternal postnatal depression may be a risk factor for later child growth faltering or overweight. A total of 929 women and their children participating in a European multicenter study were included at a median age of 14 days. Mothers completed the Edinburgh postnatal depression scale (EPDS) at 2, 3 and 6 months after delivery. EPDS scores of 13 and above at any time were defined as maternal depression. Weight, length, triceps and subscapular skinfold thicknesses were measured, and body mass index (BMI) were calculated when the children were two years old and converted to standard deviation scores based on the WHO Multicentre Growth Reference Study (MGRS). Z-scores for weight-for-length at inclusion of infants of mothers with high EPDS scores (-0.55, SD 0.74) were lower than of those with normal scores (-0.36, SD 0.74; p = 0.013). BMI at age 24 months did not differ in the high (16.3 kg/m2, SD 1.3) and in the normal EPDS groups (16.2 kg/m2, SD 1.3; p = 0.48). All other anthropometric indices also did not differ between groups, with no change by multivariate adjustment. We conclude that a high maternal postnatal depression score does not have any major effects on offspring growth in high income countries.
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