Age-related differences in working memory: ERPs reveal age-related delays in selection- and inhibition-related processes.
Age-related differences in working memory: ERPs reveal age-related delays in selection- and inhibition-related processes.
复制标题
DOI：
10.1080/13825585.2013.833581
复制
发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Friedman D
中科院分区：
文献类型：
--
作者：
Yi Y;Friedman D
fabetamine抑制与年龄相关的工作记忆下降有关。工作记忆项目选择和抑制的ERP信号分别为提示锁定的顶叶正波（~ 350 ms）和探测锁定的额叶负波（~ 520 ms）。为了确定在老年范围内选择性和抑制性过程的差异何时可能发生，在WM任务中记录了20名年轻人（20-28岁），20名10岁-老年人（60-70岁）和20名老年人（71-82岁）的ERPs。4位数字显示之后是指示4位数字中的哪2位是相关的提示。前摄干扰（PI），匹配和不匹配的被忽略的数字之间的反应时的差异较大，相对于年轻人，在两个老年组。与年轻人相比，老年组的线索锁定和探测锁定活动都延长了。虽然各年龄组之间没有地形差异，但PI和相关ERPs的延长表明抑制存在相对的年龄相关缺陷。
Faulty inhibition is implicated in age-related working memory decline. ERP signs of selection and inhibition of items in working memory (WM) are, respectively, a cue-locked parietal positivity (~ 350 ms) and a probe-locked frontal negativity (~ 520 ms). To determine when in the older age range differences in selective and inhibitory processes might occur, ERPs were recorded in a WM task from 20 young (20–28), 20 young-old (60–70) and 20 old-old (71–82) adults. A 4-digit display was followed by a cue indicating which 2 of 4 digits were relevant. Proactive interference (PI), the reaction time difference between a matching and non-matching to-be-ignored digit was larger, relative to the young, in both older groups. Compared to the young, both the cue- and probe-locked activities were prolonged in the older groups. Although there were no topographic differences among the age groups, the prolonged PI and associated ERPs suggest a relative age-related deficit in inhibition.
登录
查看更多内容
DOI：
10.1093/geronj/48.5.p225
发表时间：
1993-09-01
期刊：
JOURNALS OF GERONTOLOGY
影响因子：
--
作者：
ARBUCKLE, TY;GOLD, DP
通讯作者：
GOLD, DP
DOI：
10.1093/geronj/46.6.p346
发表时间：
1991-11-01
期刊：
JOURNALS OF GERONTOLOGY
影响因子：
--
作者：
NORMAN, S;KEMPER, S;ANAGNOPOULOS, C
通讯作者：
ANAGNOPOULOS, C
影响因子：
2.4
作者：
Robert, Christelle;Borella, Erika;de Ribaupierre, Anik
通讯作者：
de Ribaupierre, Anik
DOI：
10.1093/geronb/57.3.p223
发表时间：
2002-05-01
影响因子：
6.2
作者：
Persad, CC;Abeles, N;Denburg, NL
通讯作者：
Denburg, NL
影响因子：
2.1
作者：
De Beni, R;Palladino, P
通讯作者：
Palladino, P