Prevalence and risk factors of childhood allergic diseases in eight metropolitan cities in China: a multicenter study.
Prevalence and risk factors of childhood allergic diseases in eight metropolitan cities in China: a multicenter study.
复制标题
中国八个大城市儿童过敏性疾病患病率及危险因素：一项多中心研究
DOI：
10.1186/1471-2458-11-437
复制
发表时间：
2011-06-06
影响因子：
4.5
通讯作者：
Shen X
中科院分区：
文献类型：
--
作者：
Li F;Zhou Y;Li S;Jiang F;Jin X;Yan C;Tian Y;Zhang Y;Tong S;Shen X
在过去的二十年中进行的一些研究表明，儿童过敏性疾病在中国有增加的趋势。然而，很少有研究详细描述了这些疾病的地理差异，并探讨了这些疾病的危险因素。本研究调查了中国8个大城市哮喘、变应性鼻炎和湿疹的发病模式及其危险因素。方法2005年11 - 12月在中国8个大城市进行横断面调查。共有23791名6-13岁的儿童参与了本次调查。使用国际儿童哮喘和过敏研究（ISAAC）标准问卷中的问题来检查当前哮喘、过敏性鼻炎和湿疹的模式。采用Logistic回归分析评估儿童过敏的危险因素。结果8个城市儿童哮喘、变应性鼻炎和湿疹的平均患病率分别为3∙3%（95%置信区间（CI）： 3∙1%,3∙6%）、9∙8% （95% CI: 9∙4%,10∙2%）和5∙5% （95% CI: 5∙2%,5∙8%）。研究发现，与生活方式、心理健康和社会经济状况有关的因素与儿童过敏的患病率有关。这些风险因素在各个城市的分布不均匀，对当地患病率的影响不成比例。结论中国儿童过敏存在明显的地理差异。社会环境因素对儿童过敏患病率有重要影响；但这些影响因地区而异。因此，公共卫生政策应专门针对每个地区的当地风险因素。
BackgroundSeveral studies conducted during the past two decades suggested increasing trend of childhood allergic diseases in China. However, few studies have provided detailed description of geographic variation and explored risk factors of these diseases. This study investigated the pattern and risk factors of asthma, allergic rhinitis and eczema in eight metropolitan cities in China.MethodsWe conducted a cross-sectional survey during November-December 2005 in eight metropolitan cities in China. A total of 23791 children aged 6-13 years participated in this survey. Questions from the standard questionnaire of the International Study of Asthma and Allergies in Children (ISAAC) were used to examine the pattern of current asthma, allergic rhinitis and eczema. Logistic regression analyses were performed to assess the risk factors for childhood allergies.ResultsThe average prevalence of childhood asthma, allergic rhinitis and eczema across the eight cities was 3∙3% (95% Confidence interval (CI): 3∙1%, 3∙6%), 9∙8% (95% CI: 9∙4%, 10∙2%) and 5∙5% (95% CI: 5∙2%, 5∙8%), respectively. Factors related to lifestyle, mental health and socio-economic status were found to be associated with the prevalence of childhood allergies. These risk factors were unevenly distributed across cities and disproportionately affected the local prevalence.ConclusionsThere was apparent geographic variation of childhood allergies in China. Socio-environmental factors had strong impacts on the prevalence of childhood allergies; but these impacts differed across regions. Thus public health policies should specifically target at the local risk factors for each individual area.
登录
查看更多内容
影响因子：
168.9
作者：
Lumbiganon, Pisake;Laopaiboon, Malinee;Villar, Jose
通讯作者：
Villar, Jose
影响因子：
168.9
作者：
Asher, M. Innes;Montefort, Stephen;Williams, Hywel
通讯作者：
Williams, Hywel
影响因子：
8
作者：
Williams DR;Sternthal M;Wright RJ
通讯作者：
Wright RJ
中国的母乳喂养：评论。
影响因子：
3.5
作者：
Xu F;Qiu L;Binns CW;Liu X
通讯作者：
Liu X
影响因子：
4.8
作者：
Li, Shenghui;Jin, Xingming;Shen, Xiaoming
通讯作者：
Shen, Xiaoming