Polymerization- and solvent-induced phase separation in hydrophilic-rich dentin adhesive mimic.
Polymerization- and solvent-induced phase separation in hydrophilic-rich dentin adhesive mimic.
复制标题
聚合和溶剂诱导的富含亲水性牙本质粘合剂模拟物中的相位分离。
DOI：
10.1016/j.actbio.2014.03.001
复制
发表时间：
2014-07
影响因子：
9.7
通讯作者：
Spencer, Paulette
中科院分区：
文献类型：
--
作者：
Abedin, Farhana;Ye, Qiang;Good, Holly J.;Parthasarathy, Ranganathan;Spencer, Paulette
目前的牙科树脂在过湿脱矿胶原基质的渗透过程中经历相分离成富含疏水相和富含疏水相。这种相分离破坏了复合材料/牙齿界面处的粘结的完整性和耐久性。本研究首次确定了牙科胶粘剂模型富硅相的聚合动力学。通过在光固化之前将不同的水含量添加到由95和99重量%甲基丙烯酸羟乙酯（HEMA）和5和1重量%（2，2-双[4-（2-羟基-3-甲基丙烯酰氧基丙氧基）苯基]-丙烷（BisGMA）制成的纯树脂中来制备样品。制剂的粘度随着水含量的增加而降低。利用时间分辨傅里叶变换红外光谱仪对聚合反应动力学进行了研究。所有样品均表现出两阶段聚合行为，这在牙科树脂制剂中以前没有报道过。在10-30%wt的水含量下观察到最低的次级速率最大值。差示扫描量热法（DSC）显示了两个玻璃化转变温度的牙科粘合剂的富水相。DSC结果表明，最终聚合物结构内的不均匀性随着水含量的增加而降低。结果表明，牙科树脂的模型富脂相的反应机理涉及聚合诱导相分离（PIP）和溶剂诱导相分离（SIPs）。
Current dental resin undergoes phase separation into hydrophobic-rich and hydrophilic-rich phases during infiltration of the over-wet demineralized collagen matrix. Such phase separation undermines the integrity and durability of the bond at the composite/tooth interface. This study marks the first time that the polymerization kinetics of model hydrophilic-rich phase of dental adhesive has been determined. Samples were prepared by adding varying water content to neat resins made from 95 and 99wt% hydroxyethylmethacrylate (HEMA) and 5 and 1wt% (2,2-bis[4-(2-hydroxy-3-methacryloxypropoxy)phenyl1]-propane (BisGMA) prior to light curing. Viscosity of the formulations decreased with increased water content. The photo-polymerization kinetics study was carried out by time-resolved FTIR spectrum collector. All of the samples exhibited two-stage polymerization behavior which has not been reported previously for dental resin formulation. The lowest secondary rate maxima were observed for water content of 10-30%wt. Differential scanning calorimetry (DSC) showed two glass transition temperatures for the hydrophilic-rich phase of dental adhesive. The DSC results indicate that the heterogeneity within the final polymer structure decreased with increased water content. The results suggest a reaction mechanism involving both polymerization-induced phase separation (PIPs) and solvent-induced phase separation (SIPs) for the model hydrophilic-rich phase of dental resin.
登录
查看更多内容
影响因子：
9.7
作者：
Li, Y.;Carrera, C.;Chen, R.;Li, J.;Lenton, P.;Rudney, J. D.;Jones, R. S.;Aparicio, C.;Fok, A.
通讯作者：
Fok, A.
影响因子：
14
作者：
Chang, HH;Guo, MK;Jeng, JH
通讯作者：
Jeng, JH
DOI：
10.1002/jbm.b.10560
发表时间：
2003-07-15
影响因子：
3.4
作者：
Hashimoto, M;Tay, FR;Oguchi, H
通讯作者：
Oguchi, H
影响因子：
7.6
作者：
Chiaraputt, S.;Mai, S.;Tay, F. R.
通讯作者：
Tay, F. R.
影响因子：
5
作者：
Eliades, G;Vougiouklakis, G;Palaghias, G
通讯作者：
Palaghias, G