Vaccine development for syphilis.
Vaccine development for syphilis.
复制标题
梅毒的疫苗开发。
DOI:
10.1080/14760584.2016.1203262
复制
发表时间:
2017-01
影响因子:
6.2
通讯作者:
Cameron CE
中科院分区:
文献类型:
--
作者:
Lithgow KV;Cameron CE
Syphilis, caused by the spirochete Treponema pallidum subspecies pallidum, continues to be a globally prevalent disease despite remaining susceptible to penicillin treatment. Syphilis vaccine development is a viable preventative approach that will serve to complement public health-oriented syphilis prevention, screening and treatment initiatives to deliver a two-pronged approach to stemming disease spread worldwide. This article provides an overview of the need for development of a syphilis vaccine, summarizes significant information that has been garnered from prior syphilis vaccine studies, discusses the critical aspects of infection that would have to be targeted by a syphilis vaccine, and presents the current understanding within the field of the correlates of protection needed to be achieved through vaccination. Syphilis vaccine development should be considered a priority by industry, regulatory and funding agencies, and should be appropriately promoted and supported.
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影响因子:
3.1
作者:
CHAPEL, TA
通讯作者:
CHAPEL, TA
影响因子:
6.4
作者:
Cameron, CE;Lukehart, SA;Van Voorhis, WC
通讯作者:
Van Voorhis, WC
DOI:
10.1097/dad.0b013e3181e8b587
发表时间:
2011-07
期刊:
The American Journal of dermatopathology
影响因子:
--
作者:
Carlson JA;Dabiri G;Cribier B;Sell S
通讯作者:
Sell S
影响因子:
6.4
作者:
BAKERZANDER, SA;LUKEHART, SA
通讯作者:
LUKEHART, SA
影响因子:
3.1
作者:
Cox, David L.;Luthra, Amit;Radolf, Justin D.
通讯作者:
Radolf, Justin D.