Alcohol sensory processing and its relevance for ingestion.
Alcohol sensory processing and its relevance for ingestion.
复制标题
DOI:
10.1016/j.physbeh.2014.09.004
复制
发表时间:
2015-09-01
影响因子:
2.9
通讯作者:
Feretic B
中科院分区:
文献类型:
--
作者:
Brasser SM;Castro N;Feretic B
Alcohol possesses complex sensory attributes that are first detected by the body via sensory receptors and afferent fibers that promptly transmit signals to brain areas involved in mediating ingestive motivation, reinforcement, and addictive behavior. Given that the chemosensory cues accompanying alcohol consumption are among the most intimate, consistent, and immediate predictors of alcohol’s postabsorptive effects, with experience these stimuli also gain powerful associative incentive value to elicit craving and related physiologic changes, maintenance of ongoing alcohol use, and reinstatement of drug seeking after periods of abstinence. Despite the above, preclinical research has traditionally dichotomized alcohol’s taste and postingestive influences as independent regulators of motivation to drink. The present review summarizes current evidence regarding alcohol’s ability to directly activate peripheral and central oral chemosensory circuits, relevance for intake of the drug, and provides a framework for moving beyond a dissociation between the sensory and postabsorptive effects of alcohol to understand their neurobiological integration and significance for alcohol addiction.
登录
查看更多内容
影响因子:
56.9
作者:
Contreras, Marco;Ceric, Francisco;Torrealba, Fernando
通讯作者:
Torrealba, Fernando
影响因子:
2.3
作者:
Danilova, V;Hellekant, G
通讯作者:
Hellekant, G
DOI:
10.1097/00000374-200003000-00001
发表时间:
2000-03-01
影响因子:
3.2
作者:
Blizard, DA;McClearn, GE
通讯作者:
McClearn, GE
影响因子:
3.4
作者:
Brasser SM;Silbaugh BC;Ketchum MJ;Olney JJ;Lemon CH
通讯作者:
Lemon CH
DOI:
10.1111/j.1530-0277.1990.tb01234.x
发表时间:
1990-10-01
期刊:
ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH
影响因子:
--
作者:
BICE, PJ;KIEFER, SW
通讯作者:
KIEFER, SW