Stomach cancer survival in the United States by race and stage (2001-2009): Findings from the CONCORD-2 study.
Stomach cancer survival in the United States by race and stage (2001-2009): Findings from the CONCORD-2 study.
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作者：
Jim MA;Pinheiro PS;Carreira H;Espey DK;Wiggins CL;Weir HK
胃癌是世纪早期癌症相关死亡的主要原因，并且在美国的上个世纪中稳步下降。虽然胃癌的发病率和死亡率现在很低，但胃癌仍然是黑人、亚洲人和太平洋岛民以及美洲印第安人/阿拉斯加原住民发病率和死亡率的重要原因。CONCORD-2研究的数据用于分析年龄在15至99岁之间的男性和女性胃癌生存率，这些人在37个州被诊断出胃癌，占美国人口的80%。生存分析使用州特异性和种族特异性（白色和黑色）生命表校正背景死亡率，并使用国际癌症生存标准权重进行年龄标准化。按种族（全种族、黑人和白色）列出2001年至2003年和2004年至2009年诊断后5年的净生存率，以说明收集2004年监测、流行病学和最终结果汇总阶段2000数据的变化。在白人和黑人中，近三分之一的胃癌是在遥远的阶段被诊断出来的。2001年至2003年和2004年至2009年之间，标准化5年净生存率分别增加了26.1%和29%，并且没有观察到种族差异。1年、3年和5年生存率估计值分别为53.1%、33.8%和29%。大多数州的生存率都有所提高。分期生存率为64%（局部）、28.2%（区域）和5.3%（远处）。目前的结果表明胃癌的高死亡率，特别是在诊断后不久。虽然观察到胃癌生存率的改善，但黑人和白人的生存率仍然相对较低。通过控制既定的风险因素进行初级预防，预计将对进一步减少胃癌死亡产生最大影响。
Stomach cancer was a leading cause of cancer-related deaths early in the 20th century and has steadily declined over the last century in the United States. Although incidence and death rates are now low, stomach cancer remains an important cause of morbidity and mortality in black, Asian and Pacific Islander, and American Indian/Alaska Native populations. Data from the CONCORD-2 study were used to analyze stomach cancer survival among males and females aged 15 to 99 years who were diagnosed in 37 states covering 80% of the US population. Survival analyses were corrected for background mortality using state-specific and race-specific (white and black) life tables and age-standardized using the International Cancer Survival Standard weights. Net survival is presented up to 5 years after diagnosis by race (all, black, and white) for 2001 through 2003 and 2004 through 2009 to account for changes in collecting Surveillance, Epidemiology, and End Results Summary Stage 2000 data from 2004. Almost one-third of stomach cancers were diagnosed at a distant stage among both whites and blacks. Age-standardized 5-year net survival increased between 2001 to 2003 and 2004 to 2009 (26.1% and 29%, respectively), and no differences were observed by race. The 1-year, 3-year, and 5-year survival estimates were 53.1%, 33.8%, and 29%, respectively. Survival improved in most states. Survival by stage was 64% (local), 28.2% (regional), and 5.3% (distant). The current results indicate high fatality for stomach cancer, especially soon after diagnosis. Although improvements in stomach cancer survival were observed, survival remained relatively low for both blacks and whites. Primary prevention through the control of well-established risk factors would be expected to have the greatest impact on further reducing deaths from stomach cancer.
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影响因子：
2.6
作者：
Johnson, Christopher J.;Weir, Hannah K.;Yin, Daixin
通讯作者：
Yin, Daixin
影响因子：
50.5
作者：
Kim, J.;Sun, C. -L.;Ellenhorn, J. D. I.
通讯作者：
Ellenhorn, J. D. I.
DOI：
10.1016/j.ejca.2015.07.026
发表时间：
2015-10
期刊：
European journal of cancer (Oxford, England : 1990)
影响因子：
--
作者：
Anderson LA;Tavilla A;Brenner H;Luttmann S;Navarro C;Gavin AT;Holleczek B;Johnston BT;Cook MB;Bannon F;Sant M;EUROCARE-5 Working Group:
通讯作者：
EUROCARE-5 Working Group:
影响因子：
6.4
作者：
Mendoza, Daniel;Herrera, Phabiola;Ramirez-Ramos, Alberto
通讯作者：
Ramirez-Ramos, Alberto
影响因子：
3.7
作者：
Kim, Yuhree;Ejaz, Aslam;Pawlik, Timothy M.
通讯作者：
Pawlik, Timothy M.