The three major antigens on the surface of Plasmodium falciparum merozoites are derived from a single high molecular weight precursor.

The three major antigens on the surface of Plasmodium falciparum merozoites are derived from a single high molecular weight precursor.
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DOI:
10.1084/jem.160.2.624
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发表时间:
1984-08-01
期刊:
The Journal of experimental medicine
影响因子:
--
通讯作者:
Freeman RR
Freeman RR
中科院分区:
其他
文献类型:
--
作者:
Holder AA;Freeman RR

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195,000 mol wt 恶性疟原​​虫蛋白及其衍生的加工片段已通过单克隆抗体亲和层析纯化。针对纯化的蛋白质产生了多价抗血清,并用于鉴定与裂殖子相关的最终加工产物。存在 83,000、42,000 和 19,000 mol wt 的三个独特片段,它们代表恶性疟原虫裂殖子的主要表面抗原。
A 195,000 mol wt Plasmodium falciparum protein and processing fragments derived from it have been purified by monoclonal antibody affinity chromatography. A polyvalent antiserum has been raised against the purified protein and used to identify the terminal processing products associated with the merozoite. Three unique fragments of 83,000, 42,000, and 19,000 mol wt are present and they represent the major surface antigens of P. falciparum merozoites.
DOI: 10.1084/jem.158.5.1647
发表时间: 1983-11-01
影响因子: 15.3
作者:
Freeman, R R;Holder, A A
通讯作者: Holder, A A
DOI: 10.1038/223368a0
发表时间: 1969-01-01
期刊: NATURE
影响因子: 64.8
作者:
COHEN, S;BUTCHER, GA;CRANDALL, RB
通讯作者: CRANDALL, RB
DOI: 10.1016/0161-5890(78)90070-6
发表时间: 1978-01-01
期刊: IMMUNOCHEMISTRY
影响因子: --
作者:
EY, PL;PROWSE, SJ;JENKIN, CR
通讯作者: JENKIN, CR
DOI: 10.1017/s0031182000054482
发表时间: 1984-01-01
期刊: PARASITOLOGY
影响因子: 2.4
作者:
HOLDER, AA;FREEMAN, RR
通讯作者: FREEMAN, RR
由免疫血清和单克隆抗体识别的恶性疟原虫的生物合成和加工。
DOI: 10.1084/jem.156.5.1528
发表时间: 1982-11-01
影响因子: 15.3
作者:
Holder, A A;Freeman, R R
通讯作者: Freeman, R R