Utilization of 3D MRI for the Evaluation of Sphincter Pharyngoplasty Insertion Site in Patients With Velopharyngeal Dysfunction.
Utilization of 3D MRI for the Evaluation of Sphincter Pharyngoplasty Insertion Site in Patients With Velopharyngeal Dysfunction.
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利用 3D MRI 评估腭咽功能障碍患者咽括约肌成形术插入部位。
DOI：
10.1177/10556656211044656
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发表时间：
2022-12
期刊：
影响因子：
--
通讯作者：
Perry JL
中科院分区：
文献类型：
--
作者：
Mason KN;Riski JE;Williams JK;Jones RA;Perry JL
括约肌咽成形术是治疗腭咽功能障碍的一种外科方法。然而，手术失败经常被注意到，术后评估经常显示低置咽成形术。过去的研究没有量化咽成形术后发生的组织变化，间隙仍然与影响术后变化的患者特异性变量有关。本研究的目的是利用先进的三维成像和体积MRI数据来可视化和量化咽成形术插入部位和术后组织随时间的变化。采用前瞻性、重复测量设计评估术后颅测量和腭咽变量。影像在两个术后时间点完成。组织迁移，咽成形术的尺寸，和改变的预测因素在成像时间点进行分析。术后2 ~ 4个月咽成形术组织的初始位置与咽成形术组织的位置有显著差异。术后咽成形术组织的平均下移为6.82 mm，尽管参与者之间存在显著的差异。咽成形术体积平均减少30%。所有患者均出现咽成形术组织的下移。重力、瘢痕挛缩和患者特异性变量可能相互作用，影响术后咽成形术的最终位置。使用先进的成像方式，如3D MRI，可以量化和可视化组织变化。有必要继续确定可能影响术后下组织迁移和瘢痕挛缩量的患者特异性因素。
Sphincter pharyngoplasty is a surgical method to treat velopharyngeal dysfunction. However, surgical failure is often noted and post-operative assessment frequently reveals low-set pharyngoplasties. Past studies have not quantified pharyngoplasty tissue changes that occur post-operatively and gaps remain related to the patient-specific variables that influence post-operative change. The purpose of this study was to utilize advanced three-dimensional imaging and volumetric MRI data to visualize and quantify pharyngoplasty insertion site and post-surgical tissue changes over time. A prospective, repeated measures design was used for assessment of craniometric and velopharyngeal variables post-surgically. Imaging was completed across two post-operative time points. Tissue migration, pharyngoplasty dimensions, and predictors of change were analyzed across imaging time points. Significant differences were present between the initial location of pharyngoplasty tissue and the pharyngoplasty location 2-4 months post-operatively. The average post-operative inferior movement of pharyngoplasty tissue was 6.82 mm, although notable variability was present across participants. The pharyngoplasty volume decreased by 30%, on average. Inferior migration of the pharyngoplasty tissue was present in all patients. Gravity, scar contracture, and patient-specific variables likely interact, impacting final post-operative pharyngoplasty location. The use of advanced imaging modalities, such as 3D MRI, allows for the quantification and visualization of tissue change. There is a need for continued identification of patient-specific factors that may impact the amount of inferior tissue migration and scar contracture post-operatively.
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影响因子：
3.6
作者：
JACKSON, IT;SILVERTON, JS
通讯作者：
SILVERTON, JS
DOI：
10.1044/1092-4388(2011/10-0021
发表时间：
2011-12-01
影响因子：
2.6
作者：
Bae, Youkyung;Kuehn, David P.;Perry, Jamie L.
通讯作者：
Perry, Jamie L.
影响因子：
4.6
作者：
Juerchott A;Saleem MA;Hilgenfeld T;Freudlsperger C;Zingler S;Lux CJ;Bendszus M;Heiland S
通讯作者：
Heiland S
DOI：
10.1016/0002-9416(55)90126-3
发表时间：
1955-01-01
期刊：
AMER JOUR ORTHODONT
影响因子：
--
作者：
SUBTELNY, J. D.
通讯作者：
SUBTELNY, J. D.
影响因子：
1.8
作者：
Satoh, K;Wada, T;Shiba, R
通讯作者：
Shiba, R