Nano based drug delivery systems: recent developments and future prospects.
Nano based drug delivery systems: recent developments and future prospects.
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DOI：
10.1186/s12951-018-0392-8
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发表时间：
2018-09-19
影响因子：
10.2
通讯作者：
Shin HS
中科院分区：
文献类型：
--
作者：
Patra JK;Das G;Fraceto LF;Campos EVR;Rodriguez-Torres MDP;Acosta-Torres LS;Diaz-Torres LA;Grillo R;Swamy MK;Sharma S;Habtemariam S;Shin HS
纳米医学和纳米递送系统是一门相对较新的但发展迅速的科学，其中纳米尺度的材料被用作诊断工具的手段或以受控的方式将治疗剂递送到特定的目标部位。纳米技术在治疗慢性人类疾病方面提供了多种好处，它通过特定位点和定向靶向的精准药物递送。近年来，纳米药物（化学治疗剂、生物治疗剂、免疫治疗剂等）在各种疾病的治疗中有许多突出的应用。本综述通过对纳米材料在提高新旧药物（如天然产物）疗效和通过疾病标记分子进行选择性诊断方面的发现和应用的全面审查，对纳米医学和纳米基药物递送系统领域的最新进展进行了最新总结。本文还讨论了纳米药物在从合成/天然来源给药到临床应用方面的机遇和挑战。此外，我们还包括了有关纳米医学领域的趋势和前景的信息。
Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic agents to specific targeted sites in a controlled manner. Nanotechnology offers multiple benefits in treating chronic human diseases by site-specific, and target-oriented delivery of precise medicines. Recently, there are a number of outstanding applications of the nanomedicine (chemotherapeutic agents, biological agents, immunotherapeutic agents etc.) in the treatment of various diseases. The current review, presents an updated summary of recent advances in the field of nanomedicines and nano based drug delivery systems through comprehensive scrutiny of the discovery and application of nanomaterials in improving both the efficacy of novel and old drugs (e.g., natural products) and selective diagnosis through disease marker molecules. The opportunities and challenges of nanomedicines in drug delivery from synthetic/natural sources to their clinical applications are also discussed. In addition, we have included information regarding the trends and perspectives in nanomedicine area.
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负载百里醌的纳米结构脂质载体：制备、胃保护、体外毒性和血管外给药后的药代动力学特性。
影响因子：
8
作者：
Abdelwahab SI;Sheikh BY;Taha MM;How CW;Abdullah R;Yagoub U;El-Sunousi R;Eid EE
通讯作者：
Eid EE
影响因子：
--
作者：
Beutler, John A
通讯作者：
Beutler, John A
DOI：
10.1016/b978-0-08-100970-3.00001-8
发表时间：
2018-01-01
期刊：
BIODEGRADABLE AND BIOCOMPATIBLE POLYMER COMPOSITES: PROCESSING, PROPERTIES AND APPLICATIONS
影响因子：
--
作者：
Balaji, Anand B.;Pakalapati, Harshini;Siddiqui, Humaira
通讯作者：
Siddiqui, Humaira
DOI：
10.1016/j.ijbiomac.2016.09.008
发表时间：
2016-12-01
影响因子：
8.2
作者：
Baghbani, Fatemeh;Mortarzadeh, Fathollah;Mokhtari-Dizaji, Manijhe
通讯作者：
Mokhtari-Dizaji, Manijhe
DOI：
10.1016/b978-0-08-100262-9.00002-1
发表时间：
2017-01-01
期刊：
BIORESORBABLE POLYMERS FOR BIOMEDICAL APPLICATIONS: FROM FUNDAMENTALS TO TRANSLATIONAL MEDICINE
影响因子：
--
作者：
Bassas-Galia, M.;Follonier, S.;Zinn, M.
通讯作者：
Zinn, M.