The roles of ascending sensory signals and top-down central control in the entrainment of a locomotor CPG
The roles of ascending sensory signals and top-down central control in the entrainment of a locomotor CPG
复制标题
上行感觉信号和自上而下的中央控制在运动 CPG 的夹带中的作用
DOI:
10.1007/s00422-020-00852-8
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发表时间:
2020
影响因子:
1.9
通讯作者:
Rubin, Jonathan E.
中科院分区:
文献类型:
--
作者:
Codianni, Marcello G.;Daun, Silvia;Rubin, Jonathan E.
Previous authors have proposed two basic hypotheses about the factors that form the basis of locomotor rhythms in walking insects: sensory feedback only or sensory feedback together with rhythmic activity of small neural circuits called central pattern generators (CPGs). Here we focus on the latter. Following this concept, to generate functional outputs, locomotor control must feature both rhythm generation by CPGs at the level of individual joints and coordination of their rhythmic activities, so that all muscles are activated in an appropriate pattern. This work provides an in-depth analysis of an aspect of this coordination process based on an existing network model of stick insect locomotion. Specifically, we consider how the control system for a single joint in the stick insect leg may produce rhythmic output when subjected to ascending sensory signals from other joints in the leg. In this work, the core rhythm generating CPG component of the joint under study is represented by a classical half-center oscillator constrained by a basic set of experimental observations. While the dynamical features of this CPG, including phase transitions by escape and release, are well understood, we provide novel insights about how these transition mechanisms yield entrainment to the incoming sensory signal, how entrainment can be lost under variation of signal strength and period or other perturbations, how entrainment can be restored by modulation of tonic top-down drive levels, and how these factors impact the duty cycle of the motor output.
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影响因子:
1.2
作者:
Skinner, F K;Kopell, N;Marder, E
通讯作者:
Marder, E
影响因子:
2.5
作者:
P. Rosenbaum;J. Schmitz;Joachim Schmidt;A. Büschges
通讯作者:
A. Büschges
DOI:
10.1113/jp278031
发表时间:
2019
期刊:
The Journal of Physiology
影响因子:
--
作者:
A. Büschges
通讯作者:
A. Büschges
影响因子:
1.2
作者:
Daun, Silvia;Rubin, Jonathan E.;Rybak, Ilya A.
通讯作者:
Rybak, Ilya A.
DOI:
--
发表时间:
--
期刊:
影响因子:
--
作者:
K. Tsujita;T. Masuda
通讯作者:
T. Masuda