The Diabetes Prevention Program: recruitment methods and results.
The Diabetes Prevention Program: recruitment methods and results.
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糖尿病预防计划：招募方法和结果。
DOI：
10.1016/s0197-2456(01)00184-2
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
DPPResearchGroup
中科院分区：
文献类型：
--
作者：
Rubin,RichardR;Fujimoto,WilfredY;Marrero,DavidG;Brenneman,Tina;Charleston,JeanneB;Edelstein,SharonL;Fisher,EdwinB;Jordan,Ruth;Knowler,WilliamC;Lichterman,LynneC;Prince,Melvin;Rowe,PatriciaM;DPPResearchGroup
糖尿病预防计划（DPP）是一项多中心随机对照试验，旨在测试饮食和运动或药物治疗是否可以预防或延迟葡萄糖耐量受损患者的2型糖尿病发作，这些患者的疾病风险增加。本文介绍了民进党的招聘方法，战略，性能和成本。采购政策司建立了一个全面管理和持续监测征聘工作的组织结构。DPP采用了多种招募策略（单独或组合）以及导致随机化的分步知情同意程序。监测、分析研究范围和临床特定招募数据，并用于修改招募方法。民进党的招募工作比计划稍早完成，达到了妇女入学比例的目标，几乎达到了少数种族/族裔比例的目标。诊所在他们使用的招募策略上差异很大，这些策略也因参与者年龄，性别和种族/民族而异。每个诊所工作人员用于征聘的时间平均为每周86.8小时，大部分工作由专门负责征聘的工作人员完成。征聘一名参与人所需的工作人员时数因征聘战略而异。招募成本（不包括员工成本）约为每位随机参与者1075美元。DPP的经验为那些计划类似工作的人提供了经验教训：（1）持续评估和修订招募策略的方法是有价值的;（2）一系列招募策略可能是有用的;（3）招募潜在受试者的最有效方法可能因受试者的性别、年龄和种族/民族而异;（4）招募策略在随机分配受试者所需的工作人员时间方面有所不同;和（5）分级筛选可以更容易地识别和招募理解研究要求的志愿者。
The Diabetes Prevention Program (DPP) is a multicenter randomized controlled trial designed to test whether diet and exercise or medication can prevent or delay the onset of type 2 diabetes in persons with impaired glucose tolerance, who are at increased risk of the disease. This paper describes DPP recruitment methods, strategies, performance, and costs. The DPP developed an organizational structure for comprehensive management and continuous monitoring of recruitment efforts. The DPP utilized a variety of recruitment strategies, alone or in combination, and a stepped informed consent procedure leading to randomization. Studywide and clinic-specific recruitment data were monitored, analyzed, and used to modify recruitment approaches. DPP recruitment was completed slightly ahead of schedule, meeting goals for the proportion of women enrolled and nearly meeting goals for the proportion of racial/ethnic minorities. Clinics varied widely in the recruitment strategies they used, and these strategies also varied by participant age, gender, and race/ethnicity. Staff time devoted to recruitment averaged 86.8 hours per week per clinic, with the majority of effort by staff specifically assigned to recruitment. The number of staff hours required to recruit a participant varied by recruitment strategy. Recruitment cost (excluding staff cost) was about 1075 US dollars per randomized participant. The DPP experience offers lessons for those planning similar efforts:(1) a method for ongoing assessment and revision of recruitment strategies is valuable;(2) a range of recruitment strategies may be useful;(3) the most effective methods for recruiting potential subjects may vary according to the gender, age, and race/ethnicity of those individuals;(4) recruitment strategies vary in the amount of staff time required to randomize a participant; and (5) a stepped screening may make it easier to identify and recruit volunteers who understand the requirements of the study.
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DOI：
--
发表时间：
1982
期刊：
影响因子：
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作者：
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通讯作者：
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影响因子：
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影响因子：
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作者：
通讯作者：
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影响因子：
16.2
作者：
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通讯作者：
G. Bray;K. Polonsky;P. G. Watson;R. Goldberg;S. Haffner;R. Hamman;E. Horton;S. F. Kahn;A. Kitabchi;B. Metzger;D. Nathan;J. Olefsky;F. Pi‐Sunyer;M. Prince;R. Ratner;M. Saad;S. Jack;C. Saudek;D. Schade;H. Shamoon;R. Wing;R. Arakaki;W. C. Krowler;Bain Rp;S. Marcovina;P. Rautaharju;E. Mayer‐Davis;D. O'leary;E. Stamm
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DOI：
--
发表时间：
1979
期刊：
Clinical pharmacology and therapy
影响因子：
--
作者：
W. Agras;G. Marshall
通讯作者：
G. Marshall