The tax mutation at nucleotide 7959 of human T-cell leukemia virus type 1 (HTLV-1) is not associated with tropical spastic paraparesis/HTLV-1-associated myelopathy but is linked to the cosmopolitan molecular genotype
The tax mutation at nucleotide 7959 of human T-cell leukemia virus type 1 (HTLV-1) is not associated with tropical spastic paraparesis/HTLV-1-associated myelopathy but is linked to the cosmopolitan molecular genotype
复制标题
人类 T 细胞白血病病毒 1 型 (HTLV-1) 核苷酸 7959 处的 Tax 突变与热带痉挛性截瘫/HTLV-1 相关脊髓病无关,但与世界性分子基因型有关
DOI:
10.1128/jvi.69.9.5925-5927.1995
复制
发表时间:
1995
影响因子:
5.4
通讯作者:
A. Gessain
中科院分区:
文献类型:
--
作者:
R. Mahieux;G. de Thé;A. Gessain
The recent report by Renjifo et al. (13) suggests ‘‘that a mutation in tax nucleotide 7959 is associated with TSP/HAM [tropical spastic paraparesis/human T-cell leukemia virus type 1 (HTLV-1)-associated myelopathy] disease outcome independent of the geographical origin of the patient’’. These data relate to the critical question which has been investigated since 1990 (3, 6, 14, 16–19) of whether a hematological disorder (such as adult T-cell leukemia [ATL]) or a neurological process (such as TSP/HAM) associated with HTLV-1 is caused by a specific variant virus.We and others have demonstrated by
影响因子:
3.7
作者:
Paine,E;Garcia,J;Philpott,TC;Shaw,G;Ratner,L
通讯作者:
Ratner,L
影响因子:
1.5
作者:
Ratner,L;Philpott,T;Trowbridge,DB
通讯作者:
Trowbridge,DB
DOI:
10.1016/0923-2516(96)81078-8
发表时间:
1995
期刊:
Research in virology.
影响因子:
--
作者:
Renjifo,B;Osterman,J;Borrero,I;Essex,M
通讯作者:
Essex,M