Comorbidities and Chronic Obstructive Pulmonary Disease: Prevalence, Influence on Outcomes, and Management.
Comorbidities and Chronic Obstructive Pulmonary Disease: Prevalence, Influence on Outcomes, and Management.
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DOI：
10.1055/s-0035-1556063
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发表时间：
2015-08
影响因子：
3.2
通讯作者：
Hansel NN
中科院分区：
文献类型：
--
作者：
Putcha N;Drummond MB;Wise RA;Hansel NN
合并症影响很大一部分慢性阻塞性肺病 (COPD) 患者，估计超过 80% 的 COPD 患者至少患有一种慢性合并症。慢性阻塞性肺病的治疗指南刚刚将合并症纳入其慢性阻塞性肺病的管理建议中，而且越来越明显的是，多种疾病以及特定的合并症与慢性阻塞性肺病的死亡率和临床结果密切相关，包括呼吸困难、运动能力、生活质量、医疗保健利用和恶化风险。人们越来越关注描述 COPD 人群的合并症负担，并将这些信息纳入现有的工作中，以更好地了解该群体的临床和表型异质性。在本文中，我们总结了有关 COPD 合并症负担和特定合并症的现有知识，重点关注患病率估计、与结果的关联以及有关治疗策略的现有知识。
Comorbidities impact a large proportion of patients with chronic obstructive pulmonary disease (COPD), with over 80% of patients with COPD estimated to have at least one comorbid chronic condition. Guidelines for the treatment of COPD are just now incorporating comorbidities to their management recommendations of COPD, and it is becoming increasingly clear that multimorbidity as well as specific comorbidities have strong associations with mortality and clinical outcomes in COPD, including dyspnea, exercise capacity, quality of life, healthcare utilization, and exacerbation risk. Appropriately, there has been an increased focus upon describing the burden of comorbidity in the COPD population and incorporating this information into existing efforts to better understand the clinical and phenotypic heterogeneity of this group. In this article, we summarize existing knowledge about comorbidity burden and specific comorbidities in COPD, focusing on prevalence estimates, association with outcomes, and existing knowledge about treatment strategies.
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