Cardiovascular responses to arm static exercise in men with thoracic spinal cord lesions

Cardiovascular responses to arm static exercise in men with thoracic spinal cord lesions
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胸脊髓病变男性对手臂静态运动的心血管反应

DOI:
10.1007/s00421-011-2017-x
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发表时间:
2012
影响因子:
3
通讯作者:
F. Tajima
F. Tajima
中科院分区:
医学3区
文献类型:
--
作者:
Keiko Sakamoto;Takeshi Nakamura;Y. Umemoto;Yumi Koike;Y. Sasaki;F. Tajima

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等长肌肉收缩(静态运动)会引起循环反应。胸脊髓损伤 (TSCI) 患者的静态运动会引起心血管反应和血液重新分配到非运动肌肉。我们研究的目的是确定 TSCI 和健全 (AB) 对照个体在手臂静态锻炼期间的循环反应。无创记录平均血压 (MBP)、心率 (HR)、心输出量 (CO)、腿部皮肤血流量 (SBF) 和腿部肌肉血流量 (MBF),通过将 MBP 除以 CO 来估计总外周阻力 (TPR),并测量 7 名患者的手臂屈肌静态 35% 最大自主收缩 (MVC) 之前、期间和之后的激素变化。 患有 TSCI (T7–T11) 的男性个体和七个年龄可比的 AB 对照(分别为 32.2 ± 7.6 和 31.0 ± 4.7 岁)。 TSCI 和 AB 个体的 35% MVC 相似(分别为 107.3 ± 28.2 和 101.0 ± 22.5 N)。手臂静态运动期间,两组的 HR、CO、MBP、TPR、SBF 和 MBF 均有所增加。仅 AB 对照组的手臂静态运动期间血浆肾上腺素浓度增加(P < 0.05)。 TSCI 和 AB 个体的腿部肌肉循环相似,并且瘫痪腿部区域缺乏交感血管收缩不会改变 35% MVC 手臂静态运动期间的心血管反应。我们得出的结论是,在 35% MVC 的手臂静态运动期间,休息腿部区域的交感血管收缩不会对升压反射产生影响。
Isometric muscle contraction (static exercise) induces circulatory response. Static exercise in individuals with thoracic spinal cord injury (TSCI) induces cardiovascular response and blood redistribution to the non-exercising muscles. The aim of our study was to determine the circulatory response during arm static exercise in individuals with TSCI and able-bodied (AB) controls. Mean blood pressure (MBP), heart rate (HR), cardiac output (CO), leg skin blood flow (SBF), and leg muscle blood flow (MBF) were recorded noninvasively, total peripheral resistance (TPR) was estimated by dividing MBP by CO, and hormonal changes were measured before, during and after static 35% maximal voluntary contraction (MVC) of the arm flexor muscles in seven male individuals with TSCI (T7–T11) and seven age-comparable AB control (32.2 ± 7.6 and 31.0 ± 4.7 years, respectively). The 35% MVC was similar in TSCI and AB individuals (107.3 ± 28.2 and 101.0 ± 22.5 N, respectively). HR, CO, MBP, TPR, SBF and MBF increased in both groups during arm static exercise. Plasma epinephrine concentration increased during arm static exercise in AB controls only (P < 0.05). Circulation to leg muscles was similar in TSCI and AB individuals and the lack of sympathetic vasoconstriction in the paralyzed leg area did not alter the cardiovascular responses during 35% MVC of arm static exercise. We conclude that sympathetic vasoconstriction in the resting leg area did not contribute to the pressor reflex during 35% MVC of arm static exercise.
男性四肢瘫痪者头朝外浸水时的心血管、肾脏和内分泌反应。
DOI: 10.1152/ajpregu.1990.258.6.r1424
发表时间: 1990
期刊: The American journal of physiology
影响因子: --
作者:
Tajima,F;Sagawa,S;Iwamoto,J;Miki,K;Freund,BJ;Claybaugh,JR;Shiraki,K
通讯作者: Shiraki,K
人类持续负压呼吸期间的交感神经活动和肾脏反应。
DOI: 10.1152/ajpregu.1991.261.2.r276
发表时间: 1991
期刊: The American journal of physiology
影响因子: --
作者:
Tanaka,H;Sagawa,S;Miki,K;Tajima,F;Freund,BJ;Claybaugh,JR;Shiraki,K
通讯作者: Shiraki,K