Left ventricular infarct size, peri-infarct zone, and papillary scar measurements: A comparison of high-resolution 3D and conventional 2D late gadolinium enhancement cardiac MR.
Left ventricular infarct size, peri-infarct zone, and papillary scar measurements: A comparison of high-resolution 3D and conventional 2D late gadolinium enhancement cardiac MR.
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DOI：
10.1002/jmri.21897
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发表时间：
2009-10
影响因子：
4.4
通讯作者：
Manning, Warren J.
中科院分区：
文献类型：
--
作者：
Peters, Dana C.;Appelbaum, Evan A.;Nezafat, Reza;Dokhan, Basem;Han, Yuchi;Kissinger, Kraig V.;Goddu, Beth;Manning, Warren J.
关键词：
在既往心肌梗死患者中比较空间分辨率更高的3D晚期钆增强（LGE）心血管MR（心脏MR）与2D LGE。14例患者采用高空间分辨率三维LGE（1.3×1.3× 5.0 mm 3）和常规二维LGE（2×2× 8 mm 3）扫描。测量SNR和CNR。使用Bland-Altman分析比较总梗死体积、在有限平板中测量的梗死周围体积和乳头肌瘢痕体积。对图像质量进行分级。3D LGE具有更高的瘢痕SNR（p<0.001）、更高的心肌SNR（p=0.001）、更高的乳头状瘢痕-血液CNR（p=0.01）和更大的锐度（p=0.01）。瘢痕体积一致（2D为14.5±8.2，3D为13.2±8.8），偏倚±2 SD为0.5± 6.8 ml，p=0.59 R=0.91。梗死周围体积相关，但不如瘢痕强（p=0.40，R=0.77）。对于瘢痕更不均匀的患者，3D测量的梗死周围体积更大（2D为1.9± 1.1 ml，3D为2.4±1.6 ml，p=0.15，在匹配区域）。6/14例（42%）患者存在乳头状瘢痕，3D LGE更可靠地识别。更高的空间分辨率3D LGE可提供更清晰的图像和更高的SNR，但心肌归零更少。瘢痕体积一致，与梗死周围体积相关性较差。3D LGE在乳头肌瘢痕显示方面具有上级优势。
To compare higher spatial resolution 3D late gadolinium enhancement (LGE) cardiovascular MR (Cardiac MR) with 2D LGE in patients with prior myocardial infarction. Fourteen patients were studied using high spatial resolution 3D LGE (1.3×1.3× 5.0 mm3) and conventional 2D LGE (2×2×8mm3) scans. SNR and CNR were measured. Total infarct volume, peri-infarct volume measured in a limited slab, and papillary muscle scar volume were compared using Bland-Altman analysis. Image quality was graded. 3D LGE had higher scar SNR (p<0.001), higher myocardial SNR (p=0.001), higher papillary scar-blood CNR (p=0.01), and greater sharpness (p=0.01). The scar volumes agreed (14.5±8.2 for 2D, vs. 13.2±8.8 for 3D), with bias ±2 SDs of 0.5±6.8ml, p=0.59 R=0.91. The peri-infarct volumes correlated but less strongly than scar (p=0.40, R=0.77). For patients with more heterogeneous scar, larger peri-infarct volumes were measured by 3D (1.9±1.1ml for 2D vs. 2.4±1.6 ml for 3D, p=0.15, in the matched region). Papillary scar, present in 6/14 (42%) patients, was more confidently identified on 3D LGE. Higher spatial resolution 3D LGE provides sharper images and higher SNR, but less myocardial nulling. Scar volumes agree well, with peri-infarct volumes correlating less well. 3D LGE may be superior in visualization of papillary muscle scar.
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