Automatic postprocessing for the assessment of quantitative human myocardial perfusion using MRI
Automatic postprocessing for the assessment of quantitative human myocardial perfusion using MRI
复制标题
使用 MRI 评估定量人体心肌灌注的自动后处理
作者：
A. Weng;C. Ritter;J. Lotz;M. Beer;D. Hahn;H. Köstler
心肌灌注的定量测定目前涉及耗时的后处理。本回顾性研究提出了自动后处理，包括图像配准和图像分割，以获得区域信号强度时间课程和定量perfusion values.MethodsThe自动后处理进行了测试，在75个检查志愿者和患者，57在休息和18腺苷诱导的压力下，并与手动评估相比。在一项由10项检查组成的子研究中，手工评估的观察者间变异性进行了调查。ResultsManual评估导致灌注值的中位数为0.70 ml/g/min，范围为0.03至3.68 ml/g/min。的变异性自动和手动评估之间的差异（标准差）为0.34 ml/g/min。观察者间变异性相似，0.35 ml/g/min for all measurements.ConclusionsAutomatic evaluation was successfully applied to all datasets giving results equivalent to manual evaluation.使用自动算法，单个切片的用户交互时间可以从手动评估的25分钟减少到不到1分钟。这种减少可能使定量磁共振灌注成像成为一种常规的临床程序。
ObjectiveQuantitative determination of myocardial perfusion currently involves time-consuming postprocessing. This retrospective study presents automatic postprocessing consisting of image registration and image segmentation to obtain regional signal intensity time courses and quantitative perfusion values.MethodsThe automatic postprocessing was tested in 75 examinations in volunteers and patients, 57 at rest and 18 under adenosine-induced stress, and compared with a manual evaluation. In a substudy consisting of 10 examinations, the interobserver variability of the manual evaluation was investigated.ResultsManual evaluation resulted in perfusion values with a median of 0.70 ml/g/min ranging from 0.03 to 3.68 ml/g/min. For all 75 examinations, the variability (standard deviation of the differences) between automatic and manual evaluation was 0.34 ml/g/min. Interobserver variability was of a similar order, 0.35 ml/g/min for all measurements.ConclusionsAutomatic evaluation was successfully applied to all datasets giving results equivalent to manual evaluation. The time of user interaction for one single slice could be reduced from 25 min for manual evaluation to less than 1 min using the automatic algorithm. This reduction may allow quantitative magnetic resonance perfusion imaging to become a routine clinical procedure.
影响因子：
19.7
作者：
ATKINSON, DJ;BURSTEIN, D;EDELMAN, RR
通讯作者：
EDELMAN, RR
影响因子：
19.7
作者：
Wilke, N;JeroschHerold, M;Wilson, RF
通讯作者：
Wilson, RF