Evolution of apicomplexan secretory organelles.
Evolution of apicomplexan secretory organelles.
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DOI:
10.1016/j.ijpara.2012.09.009
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发表时间:
2012-11
影响因子:
4
通讯作者:
Duraisingh MT
中科院分区:
文献类型:
--
作者:
Gubbels MJ;Duraisingh MT
The alveolate superphylum includes many free-living and parasitic organisms, which are united by the presence of alveolar sacs lying proximal to the plasma membrane, providing cell structure. All species comprising the apicomplexan group of alveolates are parasites and have adapted to the unique requirements of the parasitic lifestyle. Here the evolution of apicomplexan secretory organelles that are involved in the critical process of egress from one cell and invasion of another is explored. The variations within the Apicomplexa and how these relate to species-specific biology will be discussed. In addition, recent studies have identified specific calcium-sensitive molecules that coordinate the various events and regulate the release of these secretory organelles within apicomplexan parasites. Some aspects of this machinery are conserved outside the Apicomplexa, and are beginning to elucidate the conserved nature of the machinery. Briefly, the relationship of this secretion machinery within the Apicomplexa will be discussed, compared with free-living and predatory alveolates, and how these might have evolved from a common ancestor.
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影响因子:
4.8
作者:
Bradley, PJ;Ward, C;Boothroyd, JC
通讯作者:
Boothroyd, JC
影响因子:
5.1
作者:
Friedrich, Reut;Yeheskel, Adva;Ashery, Uri
通讯作者:
Ashery, Uri
影响因子:
4.8
作者:
Chen, XM;Splinter, PL;LaRusso, NF
通讯作者:
LaRusso, NF
DOI:
10.1111/j.1600-0463.2009.02453.x
发表时间:
2009-05
期刊:
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
影响因子:
--
作者:
Blader IJ;Saeij JP
通讯作者:
Saeij JP
影响因子:
2.2
作者:
Coats, DW
通讯作者:
Coats, DW