Low physical activity is associated with two hypokinetic motor abnormalities in psychosis.

Low physical activity is associated with two hypokinetic motor abnormalities in psychosis.
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DOI:
10.1016/j.jpsychires.2021.11.014
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发表时间:
2022-03
影响因子:
4.8
通讯作者:
Stegmayer K
Stegmayer K
中科院分区:
医学2区
文献类型:
--
作者:
Walther S;Vladimirova I;Alexaki D;Schäppi L;Damme KSF;Mittal VA;Shankman SA;Stegmayer K

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精神分裂症患者比健康对照组有更多的久坐行为,这被认为是导致多种健康逆境的原因。年龄、药物副作用和环境是精神病患者体力活动的关键决定因素。虽然运动异常在精神病中经常被观察到,但它们与低体力活动的关联却很少受到关注。在这里,我们的目的是探讨作为一个客观的测量身体活动与临床医生评估的运动功能减退性运动障碍,如帕金森症和紧张症的体动记录仪的关联。此外,我们还研究了目前患有紧张症的患者在运动评定量表和腕动记录仪上是否与没有紧张症的患者有差异。在52例精神分裂症谱系障碍患者中,我们采用腕关节活动记录仪和紧张症、帕金森综合征和阴性综合征的评分对体力活动进行了横断面评估。样本中有严重的精神发育迟缓的人。较低的活动水平与年龄增加和紧张症和帕金森症的严重程度相关。与30名无紧张症的患者相比,22名紧张症患者的活动度较低,帕金森综合征、不自主运动和阴性症状评分较高。总的来说,这些结果表明,各种运动功能减退的运动异常与较低的体力活动有关。因此,未来的研究应确定运动功能减退运动异常和体力活动之间的关联的方向,采用纵向评估和干预试验。
Individuals with schizophrenia engage in more sedentary behavior than healthy controls, which is thought to contribute to multiple health adversities. Age, medication side effects and environment are critical determinants of physical activity in psychosis. While motor abnormalities are frequently observed in psychosis, their association with low physical activity has received little interest. Here, we aimed to explore the association of actigraphy as an objective measure of physical activity with clinician assessed hypokinetic movement disorders such as parkinsonism and catatonia. Furthermore, we studied whether patients with current catatonia would differ on motor rating scales and actigraphy from patients without catatonia. In 52 patients with schizophrenia spectrum disorders, we cross-sectionally assessed physical activity using wrist actigraphy and ratings of catatonia, parkinsonism, and negative syndrome. The sample was enriched with subjects with severe psychomotor slowing. Lower activity levels correlated with increased age and severity of catatonia and parkinsonism. The 22 patients with catatonia had lower activity as well as higher scores on parkinsonism, involuntary movements, and negative symptoms compared to the 30 patients without catatonia. Collectively, these results suggest that various hypokinetic motor abnormalities are linked to lower physical activity. Therefore, future research should determine the direction of the associations between hypokinetic motor abnormalities and physical activity using longitudinal assessments and interventional trials.
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