Fat caves: caveolae, lipid trafficking and lipid metabolism in adipocytes.

Fat caves: caveolae, lipid trafficking and lipid metabolism in adipocytes.
复制标题

DOI:
10.1016/j.tem.2011.04.001
复制
发表时间:
2011-08
影响因子:
10.9
通讯作者:
Liu, Libin
Liu, Libin
中科院分区:
医学1区
文献类型:
--
作者:
Pilch, Paul F.;Liu, Libin

文献摘要

参考文献

被引文献

相似文献

小凹是真核细胞表面的子域,之所以如此命名,是因为它们类似于小洞穴,即质膜向细胞质中的小欧米茄形内陷。它们存在于许多细胞类型中,并且在脂肪细胞中尤其丰富,表明它们在脂质代谢中发挥作用。因此,缺乏小凹的小鼠和人类脂肪细胞较小,并表现出脂肪营养不良以及其他生理异常。在这里,我们回顾了支持小窝在脂肪细胞脂质代谢中在这些结构的蛋白质和脂质组成的背景下的作用的证据。
Caveolae are subdomains of the eukaryotic cell surface that are so-called because they resemble little caves, small omega-shaped invaginations of the plasma membrane into the cytosol. They are present in many cell types and are especially abundant in adipocytes where they have been implicated as playing a role in lipid metabolism. Thus mice and humans lacking caveolae have small adipocytes and exhibit lipodystrophies along with other physiological abnormalities. Here we review the evidence supporting the role of caveolae in adipocyte lipid metabolism in the context of the protein and lipid composition of these structures.
DOI: 10.1083/jcb.152.5.1079
发表时间: 2001-03-05
期刊: The Journal of cell biology
影响因子: --
作者:
Fujimoto T;Kogo H;Ishiguro K;Tauchi K;Nomura R
通讯作者: Nomura R
DOI: 10.1083/jcb.200903053
发表时间: 2009-06-29
期刊: The Journal of cell biology
影响因子: --
作者:
Bastiani M;Liu L;Hill MM;Jedrychowski MP;Nixon SJ;Lo HP;Abankwa D;Luetterforst R;Fernandez-Rojo M;Breen MR;Gygi SP;Vinten J;Walser PJ;North KN;Hancock JF;Pilch PF;Parton RG
通讯作者: Parton RG
DOI: 10.1073/pnas.172196599
发表时间: 2002-08-20
影响因子: 11.1
作者:
Fernandez, I;Ying, YS;Anderson, RGW
通讯作者: Anderson, RGW
DOI: 10.1126/science.1062688
发表时间: 2001-09-28
期刊: SCIENCE
影响因子: 56.9
作者:
Drab, M;Verkade, P;Kurzchalia, TV
通讯作者: Kurzchalia, TV
DOI: 10.1016/j.bbalip.2009.04.002
发表时间: 2009-06
影响因子: 4.8
作者:
Bickel, Perry E.;Tansey, John T.;Welte, Michael A.
通讯作者: Welte, Michael A.