Prospective association between a Mediterranean-style dietary score in childhood and cardiometabolic risk in young adults from the ALSPAC birth cohort.
Prospective association between a Mediterranean-style dietary score in childhood and cardiometabolic risk in young adults from the ALSPAC birth cohort.
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DOI：
10.1007/s00394-021-02652-7
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发表时间：
2022-03
影响因子：
5
通讯作者：
Northstone K
中科院分区：
文献类型：
--
作者：
Buckland G;Taylor CM;Emmett PM;Johnson L;Northstone K
在雅芳父母和儿童纵向研究（ALSPAC）中，研究儿童期相对地中海式饮食评分（C-rMED）与青春期/青年期心脏代谢风险（CMR）评分之间的前瞻性关联。根据饮食日记数据计算第7、10和13年的C-rMED。使用17岁（N = 1940）和24岁（N = 1961）时的人体测量和生化数据计算CMR评分（三酰甘油、HDL胆固醇、LDL胆固醇、平均动脉压、胰岛素抵抗的稳态模型评估（HOMA-IR）和脂肪质量指数（FMI）的性别特异性对数转换z评分总和）。调整后的logistic回归模型检查了C-rMED（分类和2单位增量）与高CMR评分（≥第80百分位数）和单个CMR组分（≥第80百分位数）之间的相关性。与低C-rMED的参与者相比，13岁时的高C-rMED与24岁时具有高CMR评分的调整后几率降低32%（OR 0.68（95%CI：0.49，0.94））相关。在其他年龄段没有明显的关联。对三个年龄段的C-rMED的跟踪显示，与所有低评分相比，当儿童在7至13岁期间至少有两个高C-rMED评分时，24岁时C-rMED与CMR之间的负相关性更强（调整后OR：0.49，95% CI：0.29，0.85）。FMI和HOMA-IR是导致这种关联的主要CMR成分。青春期早期较高的地中海式饮食评分与年轻人（24奥尔兹）较好的CMR特征相关。这强调了在生命早期建立健康饮食习惯对未来心脏代谢健康的重要性。在线版本包含补充材料，可通过10.1007/s 00394 -021-02652-7获得。
To investigate the prospective association between a children’s relative Mediterranean-style diet score (C-rMED) in childhood and a Cardiometabolic Risk (CMR) score in adolescence/young adulthood in the Avon Longitudinal Study of Parents and Children (ALSPAC). A C-rMED was calculated at 7, 10 and 13 years from diet diary data. Anthropometric and biochemical data at 17 (N = 1940) and 24 years (N = 1961) were used to calculate CMR scores (sum of sex-specific log-transformed z-scores from triacylglycerol, HDL cholesterol, LDL cholesterol, mean arterial blood pressure, homeostatic model assessment of insulin resistance (HOMA-IR) and fat mass index (FMI)). Adjusted logistic regression models examined associations between C-rMED (categorical and 2-unit increments) and a high CMR score (≥ 80th percentile) and individual CMR components (≥ 80th percentile). A high C-rMED at 13 was associated with a 32% (OR 0.68 (95% CI: 0.49, 0.94)) decreased adjusted odds of having a high CMR score at 24 years, compared to participants with a low C-rMED. No associations were evident at other ages. Tracking of the C-rMED across the three ages showed a stronger negative association between C-rMED and CMR at 24 years when children had at least two high C-rMED scores from 7 to 13 years (adjusted OR: 0.49, 95% CI: 0.29, 0.85), compared to all low scores. FMI and HOMA-IR were the main CMR components contributing to this association. Higher Mediterranean-style diet scores in early adolescence were associated with a better CMR profile in young adults (24 year olds). This underscores the importance of establishing healthy eating habits early in life for future cardiometabolic health. The online version contains supplementary material available at 10.1007/s00394-021-02652-7.
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影响因子：
3.7
作者：
Casas R;Sacanella E;Urpí-Sardà M;Chiva-Blanch G;Ros E;Martínez-González MA;Covas MI;Rosa Ma Lamuela-Raventos;Salas-Salvadó J;Fiol M;Arós F;Estruch R
通讯作者：
Estruch R
影响因子：
3.6
作者：
通讯作者：
--
影响因子：
6.4
作者：
Buckland, G.;Travier, N.;Riboli, E.
通讯作者：
Riboli, E.
影响因子：
2.8
作者：
Berenson, GS
通讯作者：
Berenson, GS
DOI：
10.1016/j.numecd.2016.05.005
发表时间：
2016-09-01
影响因子：
3.9
作者：
Eloranta, A. M.;Schwab, U.;Lindi, V.
通讯作者：
Lindi, V.