The identification of different endothelial cell populations within the mouse proepicardium.
The identification of different endothelial cell populations within the mouse proepicardium.
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DOI：
10.1002/dvdy.22724
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发表时间：
2011-10
影响因子：
2.5
通讯作者：
Misra, Ravi
中科院分区：
文献类型：
--
作者：
Cossette, Stephanie;Misra, Ravi
前心外膜是一种短暂的胚胎结构，是心外膜前体冠状动脉平滑肌细胞的来源，也可能是冠状动脉内皮细胞（EC）的来源。为了更好地了解心外膜发育，对EC外观进行了系统分析。多标记分析表明，EC存在于小鼠心外膜在E9.0至E9.75。不同的EC人群被发现与肝芽，静脉窦，以及人口，似乎不与这些结构。在PE发育过程中，EC的数量和EC在不同种群内的分布有时间上的增加。这些结果表明，EC存在于心外膜冠状动脉血管发生之前，并支持一个模型，其中有一个异质性的起源EC的心外膜。
The proepicardium is a transient embryonic structure that is a source of precursors of the epicardium, coronary smooth muscle cells, and may be a source of coronary endothelial cells (EC). To better understand proepicardium development a systematic analysis of EC appearance was performed. Multiple marker analysis showed that EC are present in the mouse proepicardium at E9.0 through E9.75. Distinct populations of EC were found that were associated with the liver bud, and the sinus venosus, as well as a population that do not appear to be associated with either of these structures. There was a temporal increase in the number of EC and temporal changes in the distribution of EC within the different populations during PE development. These findings indicate that EC exist in the proepicardium prior to coronary vasculogenesis, and support a model in which there is a heterogeneous origin for EC in the proepicardium.
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影响因子：
20.3
作者：
Drake, CJ;Fleming, PA
通讯作者：
Fleming, PA
影响因子：
2.5
作者：
Männer, J;Schlueter, J;Brand, T
通讯作者：
Brand, T
影响因子：
2.5
作者：
Guadix, JA;Carmona, R;Pérez-Pomares, JM
通讯作者：
Pérez-Pomares, JM
影响因子：
2.6
作者：
Kraus, F;Haenig, B;Kispert, A
通讯作者：
Kispert, A
DOI：
10.1007/s004290050235
发表时间：
1999-04-01
期刊：
ANATOMY AND EMBRYOLOGY
影响因子：
--
作者：
Peeters, MPFMV;Gittenberger-de Groot, AC;Poelmann, RE
通讯作者：
Poelmann, RE