Selectively grafting polymer from the interior and/or exterior surfaces of bioreducible and temperature-responsive nanocapsules
Selectively grafting polymer from the interior and/or exterior surfaces of bioreducible and temperature-responsive nanocapsules
复制标题
从生物可还原和温度响应性纳米胶囊的内部和/或外部表面选择性地接枝聚合物
DOI：
10.1039/c2py20675g
复制
发表时间：
2013-01
影响因子：
4.6
通讯作者：
Yezi You
中科院分区：
文献类型：
--
作者：
Lu Yan;Zhongkai Wang;Junjie Yan;Lifen Han;Qinghui Zhou;Yezi You
报道了一种从生物可还原和温度响应的纳米胶囊的内部和/或外部表面选择性接枝聚合物刷的新策略。以N，N′-半胺双丙烯酰胺（CBA）为壳层交联剂，采用种子沉淀法分别将N-异丙烯酰胺与聚乙二醇甲基丙烯酸酯（P(NIPAM-co-PEGMA)）进行共聚，制备了内表面、外表面或两表面均含羟基的聚（N-异丙烯酰胺-聚乙二醇甲基丙烯酸酯）纳米胶囊。通过聚乙二醇甲基丙烯酸酯（PEGMA）的加入时间来控制羟基在内表面或外表面或两表面的位置。然后，用Ce4+/介导的氧化还原引发聚合将聚(2-（二甲氨基）丙烯酸乙酯（PDMAEA）刷从P（NIPAM-co-PEGMA）纳米胶囊表面接枝，通过羟基位置控制接枝位置（内表面和/或外表面）的选择性。所得纳米胶囊对温度、pH值和氧化还原反应灵敏。
A novel strategy is reported for selectively grafting polymer brushes from the interior and/or exterior surfaces of bioreducible and temperature-responsive nanocapsules. Poly(N-isopropylacrylamide-co-poly(ethylene glycol) methacrylate) (P(NIPAM-co-PEGMA)) nanocapsules with hydroxyl groups at the interior surface, exterior surface or both surfaces were first prepared via seeded precipitation copolymerization of N-isopropylacrylamide and poly(ethylene glycol) methacrylate using N,N′-cystaminebisacrylamide (CBA) as the shell crosslinker, respectively. The location of hydroxyl groups at the interior surface or exterior surface or both surfaces was controlled via the addition time of poly(ethylene glycol) methacrylate (PEGMA). Then, Ce4+/mediated redox initiated polymerization was used to graft poly(2-(dimethylamino)ethyl acrylate) (PDMAEA) brushes from the surfaces of P(NIPAM-co-PEGMA) nanocapsules with the selectivity of the grafting position (the interior and/or exterior surfaces) being controlled via hydroxyl location. The resulting nanocapsules are temperature, pH and redox responsive.
登录
查看更多内容
影响因子：
16.6
作者：
Sugihara, Shinji;Armes, Steven P.;Lewis, Andrew L.
通讯作者：
Lewis, Andrew L.
影响因子：
--
作者：
Zhongkai Wang;Di Wang;Hua Wang;Junjie Yan;Yezi You;Zhi Wang
通讯作者：
Zhongkai Wang;Di Wang;Hua Wang;Junjie Yan;Yezi You;Zhi Wang
影响因子：
29.4
作者：
B. Krause;G. Koops;van der N.F.A. Vegt;Matthias Wessling;M. Wubbenhorst;van Jan Turnhout
通讯作者：
B. Krause;G. Koops;van der N.F.A. Vegt;Matthias Wessling;M. Wubbenhorst;van Jan Turnhout
影响因子：
13.3
作者：
Guo, J;Yang, WL;Fu, SK
通讯作者：
Fu, SK
影响因子：
15
作者：
L. Dähne;S. Leporatti;E. Donath;H. Möhwald
通讯作者：
L. Dähne;S. Leporatti;E. Donath;H. Möhwald