Taste responses in the greater superficial petrosal nerve: substantial sodium salt and amiloride sensitivities demonstrated in two rat strains.
Taste responses in the greater superficial petrosal nerve: substantial sodium salt and amiloride sensitivities demonstrated in two rat strains.
复制标题
岩大浅神经的味觉反应：两种大鼠品系表现出明显的钠盐和阿米洛利敏感性。
DOI：
10.1037//0735-7044.112.4.991
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发表时间：
1998
影响因子：
1.9
通讯作者：
Hill,DL
中科院分区：
文献类型：
--
作者：
Sollars,SI;Hill,DL
大量的研究集中在鼓室索神经（CT）对味觉刺激的神经反应上。本报告研究了岩浅大神经（GSP）对盐和糖的敏感性以及阿米洛利对这些神经反应的影响。除了Sprague-Dawley （SD）大鼠具有大多数大鼠品系的典型CT反应外，我们还纳入了Fischer 344 （F344）大鼠，其对氯化钠（NaCl）的CT反应高于其他品系。在以水为冲洗剂的一系列刺激之后，用100 μM的阿米洛利溶液进行一系列刺激。GSP对NaCl、乙酸钠（NaAc）、氯化铵和蔗糖均有较高的响应；NaCl和NaAc反应被阿米洛利强烈抑制。F344对NaCl的相对反应显著高于SD大鼠。综上所述，GSP对盐和糖的刺激高度敏感，而腭味觉受体具有相当程度的阿米洛利敏感性。
A great quantity of research has focused on neural responses of the chorda tympani nerve (CT) to taste stimuli. This report examined salt and sugar sensitivity of the greater superficial petrosal nerve (GSP) and the effect of amiloride on these neural responses. In addition to Sprague-Dawley (SD) rats that have CT responses typical of most rat strains, we included Fischer 344 (F344) rats whose CT responses to sodium chloride (NaCl) are higher than those of other strains. After a stimulation series in which water served as the rinse, a series of stimuli was presented in 100 μM amiloride. The GSP was highly responsive to NaCl, sodium acetate (NaAc), ammonium chloride, and sucrose; NaCl and NaAc responses were strongly suppressed by amiloride. Relative responses to NaCl were significantly higher in F344 than in SD rats. In summary, the GSP is highly sensitive to salt and sugar stimulation, and palatal taste receptors have a considerable degree of amiloride sensitivity.
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影响因子：
3.5
作者：
Harada, S;Yamamoto, T;Kasahara, Y
通讯作者：
Kasahara, Y
双侧鼓索或舌咽神经切断后的盐味辨别。
DOI：
10.1152/ajpregu.1992.263.1.r169
发表时间：
1992
期刊：
The American journal of physiology
影响因子：
--
作者：
Spector,AC;Grill,HJ
通讯作者：
Grill,HJ
大鼠岩大浅神经响应上腭化学刺激的神经活动
影响因子：
3.5
作者：
M. S. Nejad
通讯作者：
M. S. Nejad
影响因子：
5.5
作者：
HILL, DL
通讯作者：
HILL, DL
饮食钠限制揭示了成年大鼠再生和完整味觉受体的功能可塑性。
DOI：
10.1523/jneurosci.14-05-02904.1994
发表时间：
1994
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Hill,DL;Phillips,LM
通讯作者：
Phillips,LM