National maps of the effects of particulate matter on mortality: exploring geographical variation.

National maps of the effects of particulate matter on mortality: exploring geographical variation.
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DOI:
10.1289/ehp.5181
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发表时间:
2003-01
影响因子:
10.4
通讯作者:
Samet JM
Samet JM
中科院分区:
环境科学与生态学1区
文献类型:
--
作者:
Dominici F;McDermott A;Zeger SL;Samet JM

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在本文中,我们提供了与空气动力学直径< 10微米的颗粒物(PM(10))短期暴露相关的相对死亡率的国家地图。我们报告了1987年至1994年美国88个最大的大都市地区的全因死亡率、心血管和呼吸道死亡以及其他死亡原因的结果。通过拟合每日死亡率对空气污染水平和潜在混杂因素的单独对数线性回归,获得了88个城市中每个城市与PM(10)相关的相对死亡率和统计不确定性程度的最大似然估计。我们通过拟合一个分层模型,考虑到真正的城市特定的相对率之间的空间相关性,获得贝叶斯估计的相对率。我们发现PM(10)的日变化与死亡率的日变化呈正相关。特别是,与PM(10)相关的心血管和呼吸系统死亡率的相对估计值平均大于全因和其他原因死亡率的相对估计值。心血管和呼吸系统死亡率、全因死亡率和其他原因死亡率的相对死亡率估计分别增加0.31%(95%后验区间,0.15-0.5)、0.22%(95%后验区间,0.1-0.38)和0.13%(95%后验区间,-0.05至0.29)。贝叶斯估计的城市特异性相对死亡率范围为0.23%至0.35%,心血管和呼吸系统死亡率为0.18%至0.27%,所有原因死亡率为0.10%至0.20%。跨城市影响的空间表征提供了确定可能影响PM(10)对健康影响的因素的可能性,包括颗粒特征,从而深入了解PM(10)造成不良健康影响的机制。
In this paper, we present national maps of relative rates of mortality associated with short-term exposure to particulate matter < 10 micro m in aerodynamic diameter (PM(10)). We report results for 88 of the largest metropolitan areas in the United States from 1987 to 1994 for all-cause mortality, combined cardiovascular and respiratory deaths, and other causes of mortality. Maximum likelihood estimates of the relative rate of mortality associated with PM(10)and the degree of statistical uncertainty were obtained for each of the 88 cities by fitting a separate log-linear regression of the daily mortality rate on air pollution level and potential confounders. We obtained Bayesian estimates of the relative rates by fitting a hierarchical model that takes into account spatial correlation among the true city-specific relative rates. We found that daily variations of PM(10) are positively associated with daily variations of mortality. In particular, the relative rate estimates of cardiovascular and respiratory mortality associated with PM(10) are larger on average than the relative rate estimates of all-cause and other-cause mortality. The estimated increase in the relative rate of death from cardiovascular and respiratory mortality, all-cause mortality, and other-cause mortality were 0.31% (95% posterior interval, 0.15-0.5), 0.22% (95% posterior interval, 0.1-0.38), and 0.13% (95% posterior interval, -0.05 to 0.29), respectively. Bayesian estimates of the city-specific relative rates ranged from 0.23% to 0.35% for cardiovascular and respiratory mortality, from 0.18% to 0.27% for all causes, and from 0.10% to 0.20% for other causes of mortality. The spatial characterization of effects across cities offers the potential to identify factors that could influence the effect of PM(10) on health, including particle characteristics, offering insights into mechanisms by which PM(10) causes adverse health effects.
DOI: 10.1198/016214502753479266
发表时间: 2002-03-01
影响因子: 3.7
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发表时间: 1990-10-03
影响因子: 120.7
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DOI: 10.1056/nejm200012143432401
发表时间: 2000-12-14
影响因子: 158.5
作者:
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