Cyanobacteria and cyanotoxins: from impacts on aquatic ecosystems and human health to anticarcinogenic effects.

Cyanobacteria and cyanotoxins: from impacts on aquatic ecosystems and human health to anticarcinogenic effects.
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DOI:
10.3390/toxins5101896
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发表时间:
2013-10-23
期刊:
影响因子:
4.2
通讯作者:
Oliveira-Filho EC
Oliveira-Filho EC
中科院分区:
医学2区
文献类型:
--
作者:
Zanchett G;Oliveira-Filho EC

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蓝细菌或蓝绿藻是地球上的先驱生物之一。它们发展了高效的光合作用能力,并在早期大气的演变中发挥了重要作用。它们对物种的发展和进化至关重要,在水生环境中很容易繁殖,主要是由于人类活动。富营养化环境有利于蓝藻水华的出现,不仅影响水质,而且产生剧毒代谢物。对人类的中毒和严重的慢性影响,如癌症,已有描述。另一方面,许多蓝藻属已被研究其毒素在人类细胞系中具有抗癌潜力,为未来控制人类腺癌的研究产生了有希望的结果。这篇综述介绍了关于蓝藻产生的毒素的知识,从它们的负面影响到它们的好处。
Cyanobacteria or blue-green algae are among the pioneer organisms of planet Earth. They developed an efficient photosynthetic capacity and played a significant role in the evolution of the early atmosphere. Essential for the development and evolution of species, they proliferate easily in aquatic environments, primarily due to human activities. Eutrophic environments are conducive to the appearance of cyanobacterial blooms that not only affect water quality, but also produce highly toxic metabolites. Poisoning and serious chronic effects in humans, such as cancer, have been described. On the other hand, many cyanobacterial genera have been studied for their toxins with anticancer potential in human cell lines, generating promising results for future research toward controlling human adenocarcinomas. This review presents the knowledge that has evolved on the topic of toxins produced by cyanobacteria, ranging from their negative impacts to their benefits.
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