The value of MRI for differentiating benign from malignant sex cord-stromal tumors of the ovary: emphasis on diffusion-weighted MR imaging.
The value of MRI for differentiating benign from malignant sex cord-stromal tumors of the ovary: emphasis on diffusion-weighted MR imaging.
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MRI 鉴别良恶性卵巢性索间质瘤的价值：强调弥散加权 MR 成像
DOI：
10.1186/s13048-018-0444-6
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发表时间：
2018-08-30
影响因子：
4
通讯作者：
Fan H
中科院分区：
文献类型：
--
作者：
Zhao SH;Li HM;Qiang JW;Wang DB;Fan H
目的探讨MRI对卵巢性索间质瘤(SCSTs)的鉴别诊断价值。方法对28例29例良性SCSTs和13例13例恶性SCSTs进行回顾性研究。除常规磁共振成像外，还进行了DW成像。评价DW成像信号强度，测量表观弥散系数(ADC)值。结果T2低信号和轻度强化均为良性SCST所特有。大多数恶性SCST在DW上呈高信号，而良性SCST大多呈低或中等信号(p= 0.000)。纤维瘤为ADC值最低的肿瘤(0.470 × 10− 3mm2/S)。硬化性间质瘤为ADC值最高的肿瘤(2.291 × 10− 3mm2/S)。剔除纤维瘤后，恶性鳞癌实质成分ADC值(0.825 ± 0.129 × 10− 3mm2/S)显著低于良性鳞癌(1.343 ± 0.528 × 10− 3mm2/S)(p= 0.024)。T2、DCE和DW对SCST良、恶性的鉴别诊断价值有限，准确率分别为69.0%、71.4%和78.1%。T2、DCE、DW三种序列联合应用对SCST良恶性的鉴别诊断准确率为88.0%。结论T2、DCE、DW三种序列联合应用较单独使用三种序列更有助于鉴别SCST的良、恶性。
BackgroundTo investigate MRI for differentiating benign from malignant sex cord-stromal tumors of the ovary (SCSTs) emphasizing on the value of diffusion-weighted (DW) magnetic resonance (MR) imaging.MethodsThis retrospective study included 29 benign SCSTs in 28 patients and 13 malignant SCSTs in 13 patients. DW imaging as well as conventional MR imaging was performed. Signal intensity on DW imaging was assessed and apparent diffusion coefficient (ADC) value was measured. In addition, T2 signal intensity and contrast enhancement pattern were also assessed and compared between benign and malignant SCSTs.ResultsBoth of the T2 hypointensity and mild enhancement were specific to benign SCSTs. The majority of malignant SCSTs showed high signal intensity on DW imaging, whereas most benign SCSTs showed low or moderate signal intensity (p= 0.000). Fibromas were the tumors with the lowest observed ADC value (0.470 × 10− 3mm2/s). Sclerosing stromal tumors were the tumors with the highest observed ADC value (2.291 × 10− 3mm2/s). ADC value of solid component was significantly lower in malignant SCSTs (0.825 ± 0.129 × 10− 3mm2/s) than in benign SCSTs (1.343 ± 0.528 × 10− 3mm2/s) when fibromas were excluded (p= 0.024). T2, DCE and DW imaging has a limited value on the differential diagnosis of the benign and malignant SCSTs with an accuracy of 69.0%,71.4% and 78.1% respectively. Combination of T2, DCE and DW imaging permitted the distinction with an accuracy of 88.0%.ConclusionsIt is more helpful for distinction of the benign and malignant SCSTs by combining of T2, DCE and DW imaging than using each of the three sequences independently.
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影响因子：
7.1
作者：
Outwater, EK;Marchetto, B;Wagner, BJ
通讯作者：
Wagner, BJ
影响因子：
--
作者：
Chung, Bo Mi;Park, Sung Bin;Oh, Yoon Jin
通讯作者：
Oh, Yoon Jin
影响因子：
4.4
作者：
Fujii, Shinya;Kakite, Suguru;Ogawa, Toshihide
通讯作者：
Ogawa, Toshihide
影响因子：
4.7
作者：
Gui, Ting;Cao, Dongyan;Guo, Lina
通讯作者：
Guo, Lina
影响因子：
5.5
作者：
Jung, SE;Lee, JM;Hahn, ST
通讯作者：
Hahn, ST