Bacteria-Derived Carbon Dots Inhibit Biofilm Formation of Escherichia coli without Affecting Cell Growth.

Bacteria-Derived Carbon Dots Inhibit Biofilm Formation of Escherichia coli without Affecting Cell Growth.
复制标题

细菌衍生的碳点抑制大肠杆菌生物膜形成而不影响细胞生长

DOI:
10.3389/fmicb.2018.00259
复制
发表时间:
2018
影响因子:
5.2
通讯作者:
Chen Z
Chen Z
中科院分区:
生物学2区
文献类型:
--
作者:
Lin F;Li C;Chen Z

文献摘要

参考文献

被引文献

相似文献

生物膜在许多生物医学和工业应用中是有害的,防止它们的形成一直是一个紧迫的挑战。本研究证明,从植物乳杆菌的生物质中通过一步水热炭化制备的碳点cd - lp可以防止大肠杆菌的生物膜形成。cd - lp没有抑制大肠杆菌的生长,表明其抗生物膜作用不是由于杀菌作用。此外,cd - lp不影响动物细胞AT II的生长,具有较低的细胞毒性、良好的安全性和良好的生物相容性。因此,cd - lp可以克服目前许多抗生素膜剂存在的细胞毒性问题。cd - lp是一种新型的抗生物膜材料,为生物膜处理的发展开辟了一条新的途径。
Biofilms are deleterious in many biomedical and industrial applications and prevention of their formation has been a pressing challenge. Here, carbon dots, CDs-LP that were easily synthesized from the biomass of Lactobacillus plantarum by one-step hydrothermal carbonization, were demonstrated to prevent biofilm formation of E. coli. CDs-LP did not thwart the growth of E. coli, indicating the anti-biofilm effect was not due to the bactericidal effect. Moreover, CDs-LP did not affect the growth of the animal cell AT II, showing low cytotoxicity, good safety and excellent biocompatibility. Therefore, CDs-LP could overcome the cytotoxicity issue found in many current antibiofilm agents. CDs-LP represent a new type of anti-biofilm materials, opening up a novel avenue to the development of biofilm treatment.
DOI: 10.1126/science.1176667
发表时间: 2009-08-28
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Fischbach MA;Walsh CT
通讯作者: Walsh CT
DOI: 10.1016/j.biomaterials.2016.12.011
发表时间: 2017-03-01
期刊: BIOMATERIALS
影响因子: 14
作者:
Geilich, Benjamin M.;Gelfat, Ilia;Webster, Thomas J.
通讯作者: Webster, Thomas J.
DOI: 10.1021/acsnano.5b05406
发表时间: 2016-01-01
期刊: ACS NANO
影响因子: 17.1
作者:
Ding, Hui;Yu, Shang-Bo;Xiong, Huan-Ming
通讯作者: Xiong, Huan-Ming
DOI: 10.1021/jacs.5b11834
发表时间: 2016-01-27
影响因子: 15
作者:
Joseph, Roymon;Naugolny, Alissa;Cohen, Yoram
通讯作者: Cohen, Yoram
DOI: 10.1007/s00253-009-1860-8
发表时间: 2009-03-01
影响因子: 5
作者:
Attila, Can;Ueda, Akihiro;Wood, Thomas K.
通讯作者: Wood, Thomas K.