Liquid-Liquid Phase Separation in Nucleation Process of Biomineralization.

Liquid-Liquid Phase Separation in Nucleation Process of Biomineralization.
复制标题

DOI:
10.3389/fchem.2022.834503
复制
发表时间:
2022
影响因子:
5.5
通讯作者:
Zhang S
Zhang S
中科院分区:
化学3区
文献类型:
--
作者:
Qin D;He Z;Li P;Zhang S

文献摘要

参考文献

相似文献

生物矿化是一个典型的交叉学科,吸引了生物学家、化学家和地质学家对其潜在机制的研究。越来越多的研究表明,经典成核理论并不适用于生物矿物的所有成核过程,而聚合物诱导液体前体(PILPs)等相分离结构在非经典成核过程中起着至关重要的作用。这些结构能够在生物或病理上发挥不同的作用,也可能为仿生应用提供鼓舞人心的线索。然而,由于液体前体的复杂性和跨学科性质,出现了许多混淆和争议。不同领域的研究人员可能会有不同的看法,因为术语和目前的理解状态并不是常识。因此,我们的团队查阅了最新的关于各种生物矿物成核过程的文章,以澄清对一些基本概念的最新理解,并指导新人进入这个错综复杂但充满魅力的领域。
Biomineralization is a typical interdisciplinary subject attracting biologists, chemists, and geologists to figure out its potential mechanism. A mounting number of studies have revealed that the classical nucleation theory is not suitable for all nucleation process of biominerals, and phase-separated structures such as polymer-induced liquid precursors (PILPs) play essential roles in the non-classical nucleation processes. These structures are able to play diverse roles biologically or pathologically, and could also give inspiring clues to bionic applications. However, a lot of confusion and dispute occurred due to the intricacy and interdisciplinary nature of liquid precursors. Researchers in different fields may have different opinions because the terminology and current state of understanding is not common knowledge. As a result, our team reviewed the most recent articles focusing on the nucleation processes of various biominerals to clarify the state-of-the-art understanding of some essential concepts and guide the newcomers to enter this intricate but charming field.
相位分离驱动异常的染色质循环和癌症发展。
DOI: 10.1038/s41586-021-03662-5
发表时间: 2021-07
期刊: Nature
影响因子: 64.8
作者:
Ahn JH;Davis ES;Daugird TA;Zhao S;Quiroga IY;Uryu H;Li J;Storey AJ;Tsai YH;Keeley DP;Mackintosh SG;Edmondson RD;Byrum SD;Cai L;Tackett AJ;Zheng D;Legant WR;Phanstiel DH;Wang GG
通讯作者: Wang GG
DOI: 10.1002/anie.201915350
发表时间: 2020-02-25
影响因子: 16.6
作者:
Avaro, Jonathan T.;Wolf, Stefan L. P.;Gebauer, Denis
通讯作者: Gebauer, Denis
DOI: 10.1089/ten.tec.2012.0452
发表时间: 2013-07-01
影响因子: 3
作者:
Antebi, Ben;Cheng, Xingguo;Ling, Jian
通讯作者: Ling, Jian
DOI: 10.1016/j.bone.2015.04.035
发表时间: 2015-11
期刊: Bone
影响因子: 4.1
作者:
Berendsen AD;Olsen BR
通讯作者: Olsen BR
DOI: 10.1021/bp050166
发表时间: 2006-01-01
影响因子: 2.9
作者:
Cheng, XG;Gower, LB
通讯作者: Gower, LB