Translating pharmacogenomics discoveries into the clinic: an implementation framework.

Translating pharmacogenomics discoveries into the clinic: an implementation framework.
复制标题

DOI:
10.1186/gm497
复制
发表时间:
2013
期刊:
影响因子:
12.3
通讯作者:
Gamazon ER
Gamazon ER
中科院分区:
生物学1区
文献类型:
--
作者:
Huang RS;Gamazon ER

文献摘要

参考文献

被引文献

相似文献

实施药物基因组学指导的护理有可能改善临床结果;然而,药物基因组学在临床实践中的应用仍然缓慢。部分原因是缺乏将关键发现转化为诊断测试的标准化框架。最近的一项研究描述了 Coriell 个性化医疗合作组织开发的一个综合系统,用于促进基因组发现转化为临床实践,及其在七种常用处方药中的应用。请参阅相关研究论文,http://genomemedicine.com/content/5/10/93
The implementation of pharmacogenomics-guided care has the potential to improve clinical outcomes; however, the adoption of pharmacogenomics into clinical practice remains slow. This is partly due to the lack of a standardized framework for translating key findings into diagnostic tests. A recent study describes a comprehensive system developed by the Coriell Personalized Medicine Collaborative for facilitating the translation of genomic findings into clinical practice, and its application for seven commonly prescribed drugs. See related Research paper, http://genomemedicine.com/content/5/10/93
DOI: 10.1073/pnas.0903103106
发表时间: 2009-06-09
影响因子: 11.1
作者:
Hindorff, Lucia A.;Sethupathy, Praveen;Manolio, Teri A.
通讯作者: Manolio, Teri A.
DOI: 10.1097/gim.0b013e318184137c
发表时间: 2009-01-01
影响因子: 8.8
作者:
Teutsch, Steven M.;Bradley, Linda A.;Berg, Alfred O.
通讯作者: Berg, Alfred O.
DOI: 10.1038/clpt.2011.34
发表时间: 2011-05-01
影响因子: 6.7
作者:
Swen, J. J.;Nijenhuis, M.;Guchelaar, H-J
通讯作者: Guchelaar, H-J
DOI: 10.3322/caac.20002
发表时间: 2009-01
期刊: CA: a cancer journal for clinicians
影响因子: --
作者:
Huang RS;Ratain MJ
通讯作者: Ratain MJ
DOI: 10.1186/gm499
发表时间: 2013-10-18
期刊: GENOME MEDICINE
影响因子: 12.3
作者:
Gharani, Neda;Keller, Margaret A.;Christman, Michael F.
通讯作者: Christman, Michael F.